Go for it! Rome is a great city, with lots of do. Like any city it has pros and cons. Despite what I’m going to say, I’d go back again and again.
I’d highly recommend a guided group tour of the Roman Forum and the Colosseum. Also really loved Castel Sant’Angelo. I’d book all tourist attractions in advance where you can from their websites.
If you can go in the spring time, rather than when it is very hot, I’d recommend it. It’s hot as hell in the summer.
When you go in a restaurant I’d check you can pay by card before you do. The number of places that claim their card machine is broken is ridiculous. Cover charges in restaurants are normal, factor it in when pricing even if you don’t want the bread. Do your research on Tripadvisor rather than happening upon somewhere.
I’d second PP advice on pickpockets and travelling light. Use a cross body bag inside your jacket or a bumbag. Like any major city there are pickpocketing gangs and opportunists.
Taxi is a fixed price 50€ to anywhere in the city walls or Vatican, but it’s apparently too cheap for them to make a profit. I travelled with no luggage from and to the airport (cruise passengers dropped at the airport by coach with a late flight) and both taxi experiences were horrific. On the first journey the driver was going 160kmph on the motorway and weaving like a mad person.
On the return journey I flagged a taxi and clarified in Italian that the price was fixed and the taxi driver said it’s 70€ ‘old price 50€’ when we got it. I said grabbed the tariff car hanging from the seat and pointed to the price and he reluctantly agreed. We should have got out immediately but was then subjected the most terrifying taxi journey I’ve ever been on in my life. Speeding at 200kmph, slamming on breaks, and then when we arrived at the airport he tried to con me.
my DH and DD got out the of car while I paid and he tried to claim I’d only given him 10€ instead of 50€ by slight of hand. I only had 50€ so I stood my ground. I was shaking and livid, I got out of the car and cried. A quick search online showed it’s very common.
I’m well travelled, solo as well as with others and I will never get a taxi from/to the airport in Rome ever again. I’ve done private transfers which were ok apart from risk taking driving, but we’ve agreed that in future we will get the train rather than be pay to be terrified. I’m by no means a bad passenger.
I’ve never used the metro system, but I did book an Uber once and that was absolutely fine! Lovely driver and felt safe. Very expressive though, but we were running late for a timed ticket.
Hope you have a wonderful trip OP.