We also went the other way. San Francisco to LA then onto Grand Canyon.
We were a bit jetlagged in SF but did the touristy bits. Alcatraz is well worth a visit. We didn't cycle the bridge as friends had just been and said it was like cycling at the edge of the M4.
We stayed in Monterrey for the aquarium which was amazing, especially the sea otters.
We also stayed in Pismo Beach and Santa Barbara. Both were lovely, but even then (2013) you couldn't stroll along the beach in the evening for fear of tripping over rough sleepers.
We stayed in the Hilton Santa Barbara Resort, which I wouldn't recommend. We had a ground floor sea view room which sounds nice, but unfortunately there is a main road in front and the grounds were 'open', so nothing between us and the general public other than a little wall. And there were rough sleepers in the gardens. It didn't feel safe.
In LA we stayed in Santa Monica which we loved. Beach, boardwalk, nice shops and vegetarian food. We went to an LA Dodgers baseball game which was great. Everyone was very friendly and explained what was going on.
Another highlight was the Warner Brothers tour - we're big Friends fans - but learned a lot. We keep spotting the sets in various TV shows.
We also did Hollywood. The walking tour was included in one of the value passes and was surprisingly interesting.
The best bits by far were Yosemite and Grand Canyon though.
Biggest regret was not stopping in Big Sur or near there. Friends did it and it looked stunning.
One odd place to stop is Solvang near Pismo Beach. It looks like an old European village but is all concrete!