No Soho isn’t necessarily better. But it’s a lot more “villagy”. It has some old buildings with the external fire escapes and remnants of cobbled streets. It’s a very different feel to
Midtown.
Central Park is great for the Met and 5th avenue. It’s a bit like the opposite of Soho. That’s to the South and Central Park is North. If you look at a map, mark what you want to see the most. The distances are bigger then you think from Brooklyn Bridge to Central Park. I would guard against going too far East but West has the High Line which is a “must do”, I think.
Your very best bet is to get the Lonely Planet Guide for New York. They break Manhattan down into areas and list their top things to do. So they recommend: the food scene, markets, and shopping plus the Brooklyn Bridge, The Met Museum of Art, Central Park, Empire State Building, Statue of Liberty and Ellis Island, The High Line, Broadway and Times Square, MoMA, 911 Memorial, and further afield, Williamsburg and the skyline from Governor's Island. I think you could add in Top of the Rock, Greenwich Village, East Village, Soho and Chinatown. There’s also Union Square, the Flatiron building, the Tenement Museum and the Guggenheim plus parks and people watching - the list is endless. I strongly suggest you buy the book and plan. Staying in the middle (Midtown) makes some sense! I’m going to send you a few suggestions. Next message!