How long is your flight?
Try and sit in the middle or on the aisle, that way you can't see the window and it feels more like a bus.
As i have got older and now have a child, i'm more 'concerned' (for want of a better word!) about take off. I used to be able to watch the whole thing from the window - now not so much
So i close my eyes for take off/landing and sing a little song in my head - try and remember all the words, imagine singing it at Superbowl or some such crap!
So, when i'm on the 'flying bus' i occupy myself: book, music, sudoku, magazine, guide book - whatever. About 30 mins before landing I go for a wee, otherwise they start descending and seatbelt lights go on and you can't pee until you get into the terminal.
If your dc are happy to play games, then silly words or phrases - or films, for eg - on a piece of paper as hangman while away the time really well.
Decide beforehand if you want dc to carry their passports/tickets, or if you'd prefer to have them all together.
Airport security is a GIANT pain in the neck. You neec to remove: belt, shoes (sandals/flip flops can stay on), watch, jacket/wrap. In the slidey bucket through the xray goes all of that plus any hand luggage, also keys, money, mobile phone. I recently travelled solo with my 5yo and flying out of Stansted we needed 4 trays!
If you have liquids in hand luggage (if you are checking heavy cases in - put liquids in them), you need a clear ziplock bag (can get at airport security) and each bottle can only hold 100ml. So for eg mini toothpaste, mini shampoo, mini conditioner, liquid make up, mascara - also gels. Check the airport website.
Security and immigration queues are my bugbear, once i'm through them i'm ok. A necessary evil, i suppose, although i'm not happy looking at you idiot shoe bomber
Keep thinking "in X hours i'll be on a pool chair/on the beach/in hotel shower/sitting on balcony with gin looking at Eiffel Tower/in aircon etc.
Bon voyage 