We're driving down to SW France in the summer, and DCs will be 4.5 and 2.5 years old. DH thinks we should leave late at night to get a chunk of the journey done while they're asleep.
But I think that they'll wake up as the sun does anyway, which will be early, and as neither of them are nappers it will be a very long day and we'll all have a grumpy start to the holiday.