My friend from childhood is a gifted cellist. She was recognised as a child prodigy early on and is now a highly respected concert artist -- and on the surface of things, lives a glamorous and successful life.
However. Behind closed doors, she is very insecure, has fairly severe anxiety issues, finds people in general and socialising highly stressful and I am about her only friend. 
She feels that she alienates people in everyday life through her 'weirdness' and quirks of personality. And though I do sincerely love her, I sort of of know what she means as she can be incredibly intense and has different ideas of social norms which probably does scare a lot of people off in a more everyday setting.
She has a partner but IMHO he is with her for the wrong reasons and she stays with him because she thinks that no-one in their right mind would take her on and so she is lucky to have met someone half decent who will. 
Is it too late for her to break out of this rut and find some kind of normality and loving relationship? She is 38.