Yes, ds2 has one pupil very noticeably larger than the other. I noticed it when he was 4 months, took him to the GP, who referred him to consultant.
Consultant checked him initially, was happy that ds2 was able to follow objects and focus correctly for his age, but kept him on the Opthalmology books until ds was actually able to tell him what he could see.
He was discharged from consultant last August, aged 3.10, and his sight is absolutely fine - it's just that one pupil happens to be quite a bit larger than the other. Both dilate and contract normally and he can focus perfectly, it's purely a size difference. No-one else in the family has this, although my side are very short-sighted which made me initially worried.
The only difficult bit was when the consultant put drops in ds2's eyes at the first appointment - they were to dilate the pupils so he could see into the eyes, and ds2 yelled the place down as he really hated them. I had to keep his eyes shielded from the sun for a few hours afterwards, but he was absolutely fine.
Meathmom, I'm sure your dd will be fine - but definitely go to GP for referral to put your mind at rest.