Dear Sphil.........just stumbled across your thread, I feel for you. Will she go for the next cycle, what chemo was she on? I ask this as our own nightmare started in Jan 08, not long after your mum was diagnosed. My husband was diagnosed with bowel cancer which had already spread to his liver. He had surgery to remove the bowel tumour, 3 months chemo, 5fu+oxaliplatin, then he had 60% of his liver removed, followed by another 3 months of chemo. In July last year he got an all clear scan, life retd to some sort of normality. He went for a routine ct this Jan, we were devastated to be told the cancer had retd in his liver and something had shown up in his lung. We had booked to take the kids(12yr old triplets) to Florida on May 13th, next week, were told to cancel as he would need immediate treatment. He was then offered trial chemo, the Piccolo trial, dont know if you have heard of it? He is going today for the 3rd one, it has been harsh, caused horrendous rash on his face, neck, head, driven him insane itching, in the last week he has lost his hair which has upset one of my boys terribly. His last chemo will be on the 27th, then ct, then its fingers xd, if all is well he will then go back up to Kings for further liver surgery. They are now saying that the something they picked up in the lung was an infection! My husband is now 69, 11yrs older than me. We had our trio after 3 attempts of ivf, 4 years after the death of our then only child Matthew, he collapsed and died in our garden, 3 weeks before his 15th birthday, we still have no medical explanation. Life can be very cruel, we can only live for each day, never lose a moment, its very precious. I will think of you. xx