Pasting this because it summarises what Open Medicine Foundation and Medscape have said (I subscribe to them and have ME-CFS). It's unlikely to do any harm but there's no convincing evidence for it as a treatment. Should make you feel a bit more chilled, though ...
AI Overview
Vagus nerve stimulation (VNS) is being explored as a potential treatment for chronic fatigue, particularly in the context of conditions like ME/CFS and Long COVID. Initial research suggests that stimulating the vagus nerve, possibly through devices that deliver electrical impulses to the ear (transcutaneous vagus nerve stimulation or taVNS), may improve fatigue and other symptoms by influencing the autonomic nervous system and potentially reducing inflammation. However, more research is needed to confirm the efficacy and safety of VNS for these conditions. Link
Elaboration:
Vagus Nerve and Chronic Fatigue:
The vagus nerve is a major part of the parasympathetic nervous system, which regulates functions like heart rate, digestion, and inflammation. In conditions like ME/CFS and Long COVID, there is evidence suggesting vagal dysfunction and its involvement in the pathophysiology of fatigue. Link
Transcutaneous Vagus Nerve Stimulation (taVNS):
taVNS involves stimulating the vagus nerve through electrodes placed on the skin, typically around the ear. This non-invasive method is being investigated as a way to modulate vagal activity and potentially alleviate fatigue.
Research Findings:
A study on Long COVID patients showed that non-invasive VNS over several weeks could improve fatigue and reduce inflammation, according to Newcastle University.
Preliminary studies in people with ME/CFS have shown some positive outcomes with taVNS, including improvements in fatigue, although larger, more controlled trials are needed to confirm these findings.
Some individuals with ME/CFS have reported symptom relief with manual vagus nerve stimulation techniques like deep breathing, gargling, and stimulating the diving reflex. Link
Potential Mechanisms:
VNS may impact chronic fatigue through various mechanisms, including:
Modulating the autonomic nervous system: By influencing the parasympathetic nervous system, VNS may help regulate heart rate variability and other autonomic functions that are often dysregulated in chronic fatigue conditions. Link
Reducing inflammation: The vagus nerve plays a role in regulating the inflammatory response. VNS may help reduce inflammation, which is implicated in the pathophysiology of ME/CFS and Long COVID. Link
Improving brain function: Research suggests that VNS may affect brain activity and improve cognitive function, which is often impaired in chronic fatigue. Link
Important Considerations:
Not a proven treatment: While research is promising, VNS is not yet a widely accepted or established treatment for chronic fatigue.
Individual variability: The response to VNS can vary among individuals, and some may not experience significant benefits. Link
Safety: taVNS is generally considered safe, but it's important to consult with a healthcare professional before trying it, especially if you have any underlying health conditions.
Further research is needed: More research is needed to determine the optimal parameters for VNS (e.g., stimulation frequency, duration, electrode placement) and to evaluate its long-term effects. Link
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DIY gadgets cost between £200 and £800.