My DH has gout, and he is currently on allopurinol 400 mg. His latest monthly serum urate blood test was 530 μmol/l. Which is still high; however, the GP has marked it as "normal, no further action required." But I feel he should have the dose increased to 500 mg as per the guidelines below.
According to NICE guidlines If >360μmol/l increase to 300 mg/day
o Continue monthly sUA levels, increasing by a further 100mg/day each month until sUA <360
μmol/l or maximum tolerated dose is reached (The BNF max dose = 900 mg per day,8 but
locally it has been agreed that treatment should be reviewed at 600 mg per day)
o Once sUA target is achieved, annual sUA measurements are recommended