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Doctors, Nurses, Patients - can anybody give me some answers? Desperate.

23 replies

26goingon90 · 13/10/2022 21:11

Before I start, this is definitely going to be a long winded one but stay with me here if you can šŸ˜‚

I’m absolutely desperate beyond belief for some kind of answers, advice, similar experiences - literally anything to make me feel like I’m not going completely insane. I’ve just turned 27 last month, I have 4 children. During lockdown in 2020 with loads of spare time on my hands (as much spare time as you do with 3 children at the time) I decided use that time to lose some weight & get healthier and fitter. I managed to lose 2 stone, and felt amazing for it. I was so much more energetic, and for the next 2 years I would walk miles every day, always out and about with my kids and just enjoying life.

In April/May time this year I started to notice that my feet & legs were going really, really blue. When I was cold, when I was in the shower especially, or sometimes just randomly. This then spread to my hands. After about a month, I rang the GP (NHS) feeling a bit silly for even doing so as it seemed such a minor thing. The GP assured me it was NOT normal, and I was right to ring. He ran some blood tests. All fine.

But after this it was like it snowballed. It was like somebody had flicked a switch. I was suddenly struck down with this awful fatigue, and started to get joint pain & stiffness. Started in my knees (which have clicked & popped for years) but then kinda spread to my hips, lower back, shoulders. I started getting pins & needles and numbness in my hands and feet. I also felt just generally run down + crap. I couldn’t work it out but I knew I felt rough. I started to feel cold a lot, but had some increased sweating and was also very thirsty + hungry. My first thought was diabetes. Rang the GP again, he said they’d already tested for it. It had come back normal. But they were going to run some basic rheumatoid & inflammation tests. I started to look into this more. By this point, it all seemed to fit. I had worsening joint pains, tiredness, stiffness in the morning, and by this point also had some general weakness in my legs/arms. They were all clear. I was referred to rheumatology anyway.

I was given co-codamol and naproxen. This went on for a few months, gradually worsening until I ended up in urgent care twice because of pain so bad I couldn’t take a deep breath. Both times I was put on stronger painkillers & steroids temporarily. Back to the GP - a new one who thought I had ankylosing spondylitis. The gene test for that came back negative.

After another episode of horrific pain, I had another amazing doctor at my GP practice who ran every immunology test under the sun. All clear. In fact, everything perfect really except a borderline high ALT, borderline high but normal WBC count, and a low potassium. Bizarre. At this point, I was okay as long as I was moving around. The less I moved, the worse I felt. I stiffened, I got sore, I was in pain. So I kept moving and it was awful, but bearable. I began sleeping on the sofa because night times were the worst. I tossed and turn in pain and discomfort.

Onward to my rheumatology appointment last month. He reviewed all my tests, and said they all looked fine. He said I had hyper-mobility, and would send me for a nuclear bone scan to see what was going on.

Now, during the last month or so the general stiffness/pain in joints has slightly improved. I still ache, and hurt but not unbearably. But the weakness has become horrific. My legs give way from under me and buckle, I have days where lifting a spoon can seem too much, I shake, and I have zero strength or grip whatsoever. I’ve also started to notice I feel less co-ordinated, more clumsy, just sometimes not on this planet at all. I’ve started to get weird dizzy spells where I just feel almost drunk. I don’t drink either by the way! I go light-heated, sweaty, shaky. My heart races and I feel dreadful. Last week I spent the whole night awake with the most horrific pain in my right shoulder that went all the way down my right leg. The pain was bad in my shoulder, but most worrying was the complete weakness in my leg. It kept giving way & buckling on me. I went my out of hours doctor, who gave me muscle relaxants for a ā€˜muscle spasm’ and sent me on my way.

The weakness in my leg got worse over the weak, and then for some reason I was struggling to go the toilet. I’ve always suffered from constipation mildly, however this was as if I’d lost the ability to go at all. I was sent from urgent care to A&E, who x-rayed my spine and ruled out cauda equina and sent me on my way. I disclosed to the doctor that I was worried it could be MS, so they put in a referral for a brain mri. Awaiting this. Amazing.. but I’m still poorly?! I’ve spent the last week feeling the worst I have ever felt in my life. Weak, shivery, poorly, just unable to function whatsoever.

I went to the pharmacy for laxatives, who redirected me to my doctor, who sent me BACK TO A&E.

Are you losing the will to live with my story yet? Cause this is my life at the moment. šŸ˜‚šŸ˜‚ it’s a ball.

I went back to A&E who diagnosed me with faecal impaction and sent me on my way with laxatives. But not before they’d taken my bloods and put me in the waiting room as standard. 10 minutes later they are running in for me and putting me in a private room in emergency care, telling me I’m having a hypo and I need a glucose drip fast. My blood sugar was at 3. I’d an hour before eaten a bagel with Biscoff spread because I’d felt so weak & shaky.

So I’m now at a complete and utter loss. I’m stumped, seriously. I have some healthcare/medical experience, I work in science, I’ve worked in midwifery, nursing care. I’m not a doctor but I have some knowledge there. And I’m seriously just baffled by what is wrong with me. I know for a fact I don’t have fibromyalgia. That’s all I do know. But I’ve cycled between RA, lupus, axial spondyloarthritis, diabetes, MS, ehlers-danlos. I just don’t have a clue what is wrong with me and it is completely ruining my life.

I have days where I can’t function, I crawl through the day most days. Then I have days where I think - mind over matter, I WILL get better. And I’ll go to work, or take my kids out for the day, have an amazing day. Then the next day I feel like I’ve been hit by a bus. It’s impacting my relationship, my parenting, my job, my life. I don’t know if I need a rheumatologist, a neurologist, an endocrinologist. My GP don’t seem to want to help unless I beg or hound them. I understand the pressures GPs are under before anybody says otherwise, but mine really have fallen short with me quite a few times. But I also, I understand that they seem at a loss as to what to do anymore. If anybody could help me, it would mean the world & more ā™„ļø

OP posts:
Schmordle · 13/10/2022 21:18

I’m sorry I have nothing helpful to offer, just wanted to say I’m horrified at what you’re going through, at such a young age too. You deserve better care and I can’t imagine a GP will be able to get to the bottom of this. Hoping someone more informed comes along soon.

Broadswordcalling · 13/10/2022 21:20

I haven't anything helpful to offer either as not medical. Just wanted to send you a hug whilst you feel so shit and to say I hope you get answers soon X

AgathaMystery · 13/10/2022 21:22

Bless you OP - I really feel for you. I can’t help you but I wish I could.

itsalwayscycling · 13/10/2022 21:23

It sounds pretty awful. if you have muscle weakness I would have thought a neurologist might be the best option. The only thing that potentially crossed my mind from your results is hypokalaemic periodic paralysis but it’s not something I know much (anything!) about so may not fit. Hope you get some answers.

Snoredoeurve · 13/10/2022 21:28

www.nhs.uk/conditions/postural-tachycardia-syndrome/

Hi Op
Have they considered POTs?
Often associated with Ehlers-Danlos and the blue colour of feet/ legs is dependent acrocyanosis .
Hope you get a diagnosis soon op

RedLem0nade · 13/10/2022 21:34

You poor thing! There’s a lot going on there. I am a GP but clearly I’m no expert and don’t know all your details. Plus I’m just a randomer on the internet who could be anyone really. I’ll just toss this stuff out for you to mull over and apologies if I’m way off the mark.

Initially, reading your OP, I would have wondered about some sort of vasculitis. Then the possibility of a seronegative arthritis. Among other aspects I’d then wonder about what caused that hypoglycaemia. Have they checked for Addison’s disease do you know?

I hope you get sorted soon. To be fair it’s very complex. I’m not surprised your GP is hitting a wall. I hope they find the answer for you Flowers

hopelesslydevotedtoGu · 13/10/2022 21:36

Do you know if adrenal insufficiency has been considered? Relevant initial blood test would be early morning cortisol

ParsleyTL · 13/10/2022 21:40

Well, that sucks. I’m so sorry. ā˜¹ļø Has anyone done a mri of your lower spine to see if your sciatic nerve is impcted by ev soine hernia? That would fit with the leg weakness and actually the increased execise might also be linked. I kniw they x-rayed to check for cauda equina but notnsure if they did a mri to look at the status of the nerve. I’d get that looked asap, privately if necessary.

ParsleyTL · 13/10/2022 21:40

Meant to type ā€œimpacted by spine herniaā€

Thegroaninggurner · 13/10/2022 21:40

Have you had your thyroid checked?

hairyfail · 13/10/2022 21:55

Have you had a ct in a and e? Some symptoms could be vasculitis- there are many types and differing symptoms, it doesn't necessarily show on bloods but rather with symptoms and can also be co morbid with Hypermobility

IncessantNameChanger · 13/10/2022 22:19

MS might fit the weakness, but the MRI will show that. Have you had a nerve conduction test? Leg doppler?

I have various weird health things going on which my gp has washed their hands of, but I'm going back on Monday.

I'm beginning to see that I might have two conditions or more. So don't rule that possibility out. Nerve conduction, mri and dopplers can rule things out as well as in.

Have they checked all your vitamin D, b? Etc? Even borderline ok can be way too low. I had crushing fatigue. It was sleep apnea but also vitamin D which once I was supplemented made me feel 100 times better even though I was within normal range.

I'm also going to gather all of my tests and see a private gp to be honest.

Lots of people love my gp, but I'm not quite dead yet so in the nhs eyes in ok, yet I'm loosing my sight with 4 young kids and almost falling asleep at the wheel twice now. But I'm not blind. I didn't crash therefore it's fine. Until its too late

Doublevodka · 13/10/2022 22:22

That sounds horrendous OP and I’m sorry you’re having such an awful time. I’m no expert but I am a nurse and had some similar symptoms to you for many months, that started around 8 years ago. I had horrendous joint pain, weakness and 2 stone weight loss. These were the main symptoms but I had lots of other symptoms too.

I was referred to a rheumatologist and they were scratching their heads for months. I had every test known to man, including multiple scans, blood tests and a bone marrow biopsy. My bloods were normal for quite a while but then as I became more unwell they suddenly went massively out of range. Anyway, I have an aggressive form of inflammatory arthritis, but it’s not rheumatoid arthritis although very similar. I’m on a cocktail of tablets, weekly injections and a monthly IV infusion that keeps me functioning, which I’m very grateful for. I had 4 years of remission which was amazing but then had a second flare up so they had to tweak some of my drugs.

What I do know is that there are many auto immune conditions with similar symptoms and it can sometimes take quite a while for the experts to give a firm diagnosis. It took about a year for my diagnosis. I think you definitely need to stay under a rheumatologist while they try and get to the bottom of it and I think you should ask the GP to consider a neurologist referral too. I know it’s really hard when you are in so much pain daily but hang in there and keep pushing for answers.

poppymaewrite · 13/10/2022 22:57

I think it’s interesting that you started experiencing these problems after you made changes to what you eat.

It might well be related. Sometimes when people go on diets, they start eating more animal protein under the belief that this will help them. It might be great for weight loss, bit consuming animal protein is stronly linked to autoimmune diseases.

Don’t write it off as being the cause behind this. I suffered from debilitating health problems before going vegan. My only regret is not doing it sooner.

GreatBigBeautifulTommorow · 15/10/2022 08:40

I agree re adrenal insufficiency. Have you had a 9am cortisol checked?

Notaboutthebass · 15/10/2022 10:42

I have Ankylosing Spondylitis/Inflammatory Arthritis and Lupus. Your symptoms sounds the same as mine. Took years to diagnose both. Do you have problems in your sacroilliac joints too? I think you should have more scans and more specific bloods tests. I was negative for hla-b27 and ANA but had other positive antibodies.

dizzydizzydizzy · 15/10/2022 17:16

My thoughts are EDS, MS and CFS/ME.

I have the latter and you sound very much like me. My friend has EDS and she is similar. It was at first thought that I had MS. I had a lumbar puncture and tbat was normal. Head and spine MRI also normal.

lljkk · 15/10/2022 17:42

Why did you have hypo in A&E : do you have zero idea?

I think these things were tested / ruled out:

T2 diabetes: by blood test
some rheumatoid & inflammation conditions : by blood test and presentation (OP has seen a consultant)
anything immunological that can be detected with tests
ankylosing spondylitis: neither genes nor any inflammation can be detected

With OP being repeatedly tested for so many things, how likely is it that she has any of these problems after all?

Do you have any other risk factors for ill health like ... do you smoke, is your BMI still high, family history, alcohol intake, etc?

Disclaimer: am not medically qualified.

BirdsAndButterflies · 16/10/2022 08:31

Two thoughts. Could it be fluoroquinolone toxicity syndrome? Do you remember taking Cipro/levequin or similar antibiotic prior to onset of all the symptoms? It can cause so many seemingly unconnected horrendous symptoms that never show in blood tests.
the other thought is vaccine reaction (yes, I know, rare....but they do happen). I have a colleague who was hospitalised with CIDP (www.hopkinsmedicine.org/health/conditions-and-diseases/chronic-inflammatory-demyelinating-polyradiculoneuropathy?amp=true) after her second Pfizer jab.

ginpig · 16/10/2022 08:54

Not a medic but DH is....he syas doesnt sound like MS (he's a neurologist) but wonders if it might be Addison's disease , which would fit with some of the test results you've had (ALT) and would fit with the hypo. There is a test that can be done for it but unlikely to be accessible via GP and you would probably need a referral to endocrinology.

Hope you get sorted soon

CoffeethenCrochet · 17/10/2022 01:14

Definitely ask for a 9am cortisol test which can be done at G.P, then ask for referral to endocrinology for a short synacthen test.

Adrenal insufficiency/ addisons disease is often missed but ticks a lot of your symptoms. I have it (also have arthritis), I know how tough it is until diagnosis and then getting it under control. It can be done though, hang in there. Make sure you keep something sugary with you in handbag incase of another hypo. Good luck. Happy to answer any questions you have.

26goingon90 · 20/10/2022 20:36

Firstly, thank you from the bottom of my heart for everybody who has taken the time to not only read but reply to my post ā™„ļø

All my ANA, ESR, dsDNA, antibodies to CCP were negative. However this was a few months ago, and from what I have read it can change.

I can’t even tell you how much it means to me that you’ve all replied to my post - the advice and information you’ve given me is absolutely invaluable and I appreciate it so much. Makes me feel much less alone at a really crap time.

••• Just as an update if it offers anything •••
Things are finally starting to show in my bloods at long last.
Awaiting speaking to my GP/rheumatologist to discuss but my blood test from last week showed:
CRP of 21 (previously 0.3 consistently)
Raised ALT & alkaline phosphatase
Low WBC & low neutrophils
Borderline red blood cell count & haemoglobin

Not sure if that helps anyone, but I’m praying that they can find some answers for me now.

Thank you, you truly beautiful people ā™„ļøā™„ļø

OP posts:
Afterfire · 20/10/2022 20:39

CoffeethenCrochet · 17/10/2022 01:14

Definitely ask for a 9am cortisol test which can be done at G.P, then ask for referral to endocrinology for a short synacthen test.

Adrenal insufficiency/ addisons disease is often missed but ticks a lot of your symptoms. I have it (also have arthritis), I know how tough it is until diagnosis and then getting it under control. It can be done though, hang in there. Make sure you keep something sugary with you in handbag incase of another hypo. Good luck. Happy to answer any questions you have.

I was going to say the same thing.

It took me 2 years of misdiagnosis to be finally diagnosed with Addison’s. They even prescribed me diazepam and said I had panic disorder!

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