its probably just co-incidence, dd has had bloody awful cold for about a week, i was givng her medised at bed times, she has a long daytime nap usually so given at night and in afternoon. This was given to help dry up the streaming nose and also help the poor mite sleep. The past couple of afternoons when she has had medised dd has woken from her nap in a distraught state and her temperature seemed higher than before medicating. I'm sure its just because the cold was getting her down but i switched to calpol and she was much better and happier. Has anyone else experienced similar, it is enough for me to think twice about using it again but dont want to report it as a side effect as too many other factors involved. She seemed to sleep better with just the calpol, previous use of medised has not caused a problem but usually only used it for one night. This time about 3 days.