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Can anyone explain bllod groups to me please?

11 replies

FabCatsMum · 02/02/2012 12:01

DH is A RH Negative and I am O RH Positive. What does that mean my children's groups will be please?

OP posts:
LeMousquetaireAnonyme · 02/02/2012 12:08

A/o +/- wil be A +

your husband could be A/o -/- in that case you can have a o/o +/- child which will be O +

Or you could be o/o +/-
in which case you can also have a A- or an O- child.

FabCatsMum · 02/02/2012 12:40

I am so Confused but thank you for replying. Do I need to know my children's blood groups and what happens if they have another accident and need blood if I can't remember our groups?

OP posts:
sittinginthesun · 02/02/2012 12:43

I wouldn't worry. Mist people don't give it a thought. I only found our when I was pregnant (I am A negative), and they tested my boys at birth because I may have needed another jab if they were positive. I think it's easy enough for them to check.

FabCatsMum · 02/02/2012 12:45

Thank you. I just found out blood donor cards and it worried me a bit that I am positive and DH is negative and thought they might not work together.

OP posts:
sittinginthesun · 02/02/2012 13:18

It's only a worry if the mother is negative. They pick it up on the first set of bloods they take, and then give you a series of injections during the pregnancy.

LeMousquetaireAnonyme · 02/02/2012 14:26

Sorry fab but you can't guess with just the mum or dad blood group. only if you were both O - they would be sure that all your DC would be O-. But even in that case they would test before (as they can't be absolutely sure that the dad is the dad, IYSWIM). If they don't have time to check hospital give O- blood which is the universal donor.
The tests are however really quick to do and require only a drop of blood.
There is no worry about one being positive and the other one negative (only at child birth and the other way around: i.e. it can cause problem if the mother is - and the dad +).

gasman · 02/02/2012 16:29

Firstly - don't worry about remembering blood groups. In hospital if we need to give blood (except in dire dire emergencies) we always run screening tests to ensure compatibility of blood. In dire emergencies we give O negative blood which is perfectly acceptable to virtually all of the population on the

For the tiny number of people who will have a reaction the argument is essentially that if you need blood under those circumstances then the risk of not having a transfusion is much much greater than the risk of a minor blood group transfusion reaction and that proper cross matched blood for people with minor group antibodies is often difficult to get so not usually possible in an emergency most of their circulating blood volume is on the floor situation.

If you are interested NZ blood have a useful bit on their website which explain inheritance of blood groups.

www.nzblood.co.nz/Give-blood/About-blood/Inheritance-of-blood-groups

Basically each person has 46 chromosomes - arranged as 23 pairs. We all inherit 23 chromosomes from each parent. This is how sex selection by men comes about as women always have XX as their 23rd pair of chromosomes. Men however have XY. To be a boy you have to get an X from your Mum (you can't get anything else) and a Y from you Dad. To be a girl you get X from your Mother and X from your Dad. I digress.

WRT blood groups there are 3 forms of genetic information A, B and O. A and B are what is known as dominant. This means that even if you only have one copy of that information you will have that blood group. Therefore if you are blood group A you can either have the genetic information A A or A O. The same applies to B (i.e. B B or B O). O is recessive so in order to have blood group O you MUST have two copies of the O information so you can only be O O. Rhesus is also negative (but there are only two kinds of info positive + or negative -). Therefore a Rhesus positive person may be either ++ or +-. But a negative person must be - - .

Therefore without knowing exactly what genes each parent has it is difficult to predict blood group for children which is why we test. It is also a proven fact that there are a number of people in the UK whose biological parents are not actually the people they think they are (non paternity) so it is safer to test the person in front of you.

Clinically knowing that you are rhesus negative is useful for girls, especially when they get to child bearing age as even if they have a termination or early miscarriage they should get anti D injections to prevent them developing Rhesus antibodies which can cause problems for future pregnancy. There is an extensive program to make sure these injections aren't missed but I still bang on about it to my friends Rhesus negative teenagers. No one has a better incentive to look after health than the person concerned.

This is really long but I hope it vaguely makes sense. Someone on here works in a transfusion lab and knows masses more than me so will probably be along to correct me!

FabCatsMum · 02/02/2012 17:19

Thank you very much to all of you for taking the tim to answer me. I feel very stupid that I don't know about stuff like this.

OP posts:
LeMousquetaireAnonyme · 02/02/2012 17:23

Don't fell stupid, I have a degree in biology and actually done blood tests before.
"If you judge a fish by its ability to climb trees he will spend his whole life thinking he is stupid" (Einstein, may be?)

cerys74 · 02/02/2012 17:24

Please don't feel stupid Fab - I didn't know either, which is why I clicked on this thread! It would be stupid NOT to ask a question about things like this, so thanks for doing it for the rest of us :)

Gasman - that is really detailed, thanks!

cerys74 · 02/02/2012 17:30

Just remembered an interesting blood group fact: there is a small amount of speculation amongst historians that Anne Boleyn might have been Rhesus negative, as she only carried one baby to term and that was her first (Elizabeth, of course)! She miscarried several times after that in swift succession, which would fit in with a rhesus neg diagnosis. But of course we'll never know...

Apologies for the digression but it's the only bit of blood group trivia I know!

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