Drug over reactions & M.E. Fibromyalgia???

[rockinhippy]

I'm just wondering if any of the rest of you with these conditions have this problem, or if it can be a sign of something else

I rarely can tolerate any medications bar the simplest, oldest tried & tested ones & still get side effects from those

my GP who knows this & is very good at working around this as best sh ecan having seen me have some very severe reactions, is now on Maternity leave, so I have a new GP

Gastro problems, heatburn, etc been very bad lately, I feel this is partly down to side effects of BP med, but going to see the new GP, she does seem a lot more thorough & insisted I took a drug for it -Omeprazole - telling me she can see I've had a reaction to it before, but its important I take it as it will help her determine what is causing the GERD symptoms - (I'm pretty sure its an undiagnosed hernia, but thats a whole nother thread)

Anyway due to rupturing my achilles tendon & needing to rely heavily on opiate pain killers & diazepam I didn't start the drug straight away, had a few days clear of the heavy duty drugs & took the first Omerprazole last night

OMG one pill had me so bad that on speaking with out of hours GP they wanted to send me an ambulance - not really practical with DH up at 5 for work & DD in bed - but it was basically like taking a mixture of LSD & bad speed (mispent youth -

it kept hitting me in waves, hitting me at its worst just after I got into bed - DH was already asleep & i was so disorientated that when I got up & rang the Dr - amongst other things the whole bed was "breathing" I couldn't even remember my own name or date of birth, took me a few minutes to pull myself together.

having explained my situation with DH & DD & not wanting to go to A&E unless a real emergency the DR talked me through what to look out for & when to dial 999, I'd passed 1 of the key signs 4 hours earlier & hadn't actually realised, they wanted to send an ambulance, but I felt that danger had passed & they agreed on condition if it came again or any other key danger signs I sat by the phone & rang 999 - he also explained I would be up all night & feel agitated - understatement or what- I felt a weird, both very sleepy & very hyper, halucinating badly, pins & needles numb tongue swelling, with raging headache & nausea etc etc

I STILL don't feel right now & the lack of sleep has knocked me for 6 FM & ME wise :(

I don't remember what reaction I had to this drug first time around, but pretty sure I would of remembered had it been THAT bad - but now annoyed the new GP still prescribed it despite my old GP noting it asa drug not to give me

This is pretty much the story of my life with medications - I don't like taking them, & treat them with utmost respect but still have had more than my fair shaare of the worst posssible side effects

Is this something you all deal with too??, or are there other possibilities as to why I always react so badly & get the rarest of side effects no matter what

Thanks :)

Rockinhippy, how frightening No wonder your systems knocked back.

I have fibro and graves disease, take amatriptyline , omaprazole, bisoprolol, tramadol all with few side effects whatsoever but if I so much as sniff an antihystamine I start having severe palpitations and chest pain.

I wonder what's in omaprazole that triggers this. Or does sound like you have very sensitive reactions to drugs. What a position to be in!

Just realised though, I only started with the heartburn after going on the beta blockers, for blood pressure and palpitations/tachycardia. I wonder if that's the case for you. What bp meds are you on?

"2. Many patients with ME/CFS are hypersensitive to medications given in the usual doses. Always start at a lower dose than recommended and gradually build up, to determine tolerability. Add or subtract remedies one at a time, and give remedies enough time to show their effects, and exclude non-specific ?placebo? effects (approximately three months). Keep testing them to see if they are still necessary. Be careful of the addictive potential of benzodiazepines for some patients."

from www.mefmaction.com/images/stories/Medical/ME-CFS-Consensus-Document.pdf

Thanks Kate, that is brilliant, I've got to admit, as I got the Fibro Diagnosis first & only had M.E. added years later, as I kept bugging my GP for answers as not all my symptoms fit FM & I hoped for something treatable, I haven't researched into M.E as much as I did Fibromyalgia, I think by the time I'd had ME/CFS added I'd pretty much researched myself out & they seemed to be pretty much the same thing with different names

funny though, as over time I've had problems with a lot of drugs & my usual GP has realised that too & is pretty good at not giving me anything she's not sure about, but still had some scary reactions to even the tried & tested stuff,

so I've learned to start myself on half or even quarter dose & stagger the full dose with pretty much everything - makes a lot of sense now, especially as I already know I'm hypersensitive to cleaning chemicals etc - interesting - thanks again :)

Perfume I'm on Ibersartan?(aprovel) & 1 of the listed side effects IS reflux etc - though I've been tried with several others & the side effects showed up pretty much straight away & severe with it, this one seemed to be okay for the first few days & then I just put my extra aches & pains etc etc down to it been Winter & I always feel worse in Winter, but just not feeling better with better weather & having tight muscle problems that are now resulting in injury(back in A&E today, with torn calf muscle & now on crutches)

so more recently I've had a closer look at the side effects & realise a lot are symptoms of Fibro/CFS, that & my reflux problems getting worse & worse - I took myself off them for a short while & noticed a difference in joint pain, skin problems & heartburn pretty much straight away - my BP has been very high, so I wasn't silly & did start back on them - & the symptoms came back after a few days, so seems the side effects on these are accumulative, so looks like its back to the drawing board :( though I did have GERD problems before, but never this bad, causing permanent sore throat & cough now - all adding to lack of sleep [rollseyes] - glad you are coping better with yours though, but still might be worth you looking into

reading the pack there is only Omaprozole, in them didn't sleep for almost 2 full nights as a result of taking jus the 1 & as I said above, scary side effects, so yes hypersensitive as hallucinating, agitated, heart racing & everything