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Question for Tamum

33 replies

happymerryberries · 22/08/2005 18:07

How does mosaicism happen? If the extra chromosome 'lost' in some of the cells in the Blastocyst?

OP posts:
cod · 22/08/2005 18:08

Message withdrawn

Fio2 · 22/08/2005 18:09

wow what a question, hope tamum is around

why dont you email each other, then again i couldnt read your fascinating discussions

happymerryberries · 22/08/2005 18:10

Blow me some fishy bubbles!? Pleeese?

OP posts:
cod · 22/08/2005 18:10

Message withdrawn

Twiglett · 22/08/2005 18:10

hmm I could explain but I don't think your brain would be able to handle it

happymerryberries · 22/08/2005 18:10

I could Fio, but this question just occured to me after reading one of Tamums answers!

Hope no-one minds my asking online....thought it was quicker

OP posts:
cod · 22/08/2005 18:11

Message withdrawn

happymerryberries · 22/08/2005 18:11

Twiglett, if you hear a bang you'll know you were right!

OP posts:
Twiglett · 22/08/2005 18:12

I love google

happymerryberries · 22/08/2005 18:16

Thabk you, I get it know. I was foolishly discounting non dysjunction during mitosis!

OP posts:
happymerryberries · 22/08/2005 18:16

PS

BANG

OP posts:
Twiglett · 22/08/2005 18:16

pshaw how foolish of you

tamum · 22/08/2005 18:17

Helloooo

I have always assumed that there is non-disjunction occurring after one of the first cell divisions so that you get a mixture. I think that's more likely than chromosome loss, isn't it?

Sorry, sorry, I know that sounds really poncey and show-offy, it's just easier to use the proper terms

tamum · 22/08/2005 18:18

Gawd, beaten to it by Twiglett. Will I ever live this down

happymerryberries · 22/08/2005 18:19

You failed me!

Pshaw!

OP posts:
Twiglett · 22/08/2005 18:19

snurk

hang on a second .. that backfired on me .... Oy ...

happymerryberries · 22/08/2005 18:20

Can we get an emoticon for snurk

Such a good word!

OP posts:
tamum · 22/08/2005 18:27
Grin
expatinscotland · 22/08/2005 18:55

Oh, oh! I have a question about mosaicism!!! Is mosaiciasm the reason you get calico cats?? I heard about 'X inactivation', does that result in the calico cat's mosaic coat? Is that why calicos are female cats?

tamum · 22/08/2005 19:02

That's right, expat. With calico cats they have exactly the same chromosome constitution in all cells, but one of the X chromosomes is inactivated at random (this always happens). Depending on which one is inactivated, you get patches of colour. The patches have all originated from a single cell with, say, the X chromosome with the mutant version of the gene on. One of the Xs has to be inactivated because otherwise females would get a double dose of the genes on the X chromosome compared with males. Lordy, I'll be teaching this for real soon......

Hello BTW

happymerryberries · 22/08/2005 19:06

Aint MN wonderful?!

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expatinscotland · 22/08/2005 19:10

Cool, tamum! You'll be great at it! I figured out a fun way once to teach ions to teens. I made out that the charged cells felt like they were missing something in life. And when they found their other half, they were happy. Dorky, but apparently worked to help them remember for their exams!

happymerryberries · 22/08/2005 19:26

I do the same thing with displacement reactions. The compount is 'The happy couple', if a more reactive (good looking) metal comes along, Ms Cation dumps her original partner and makes a new bond!

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expatinscotland · 22/08/2005 20:23

That's it, HMB! The compound. Also, atoms are slags, they go with what makes 'em happy, even if they're related. Some are such "ho's" they need more than one babe to make 'em happy.

I did bonds as one night-stands, 'just keeping it casual', long-term relationships, marriages, etc.

I haven't noticed many calico cats around here. My mum's good friend had one for years - she lived to be about 19. She was called 'Patches' and was the sweetest of moggies. Well, aside from our two .

motherinferior · 22/08/2005 20:25

Do you know, I understood all the individual words in that and absolutely none of how it all works. As my mum would say, 'darling, you are clever'

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