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Anyone on mood stabilisers?

31 replies

PennyJenny77 · 21/11/2025 20:56

For depression? I saw my psychiatrist this morning. She's keen to put me on mood stabilisers as I keep having episodes of severe depression. It comes and goes. In between I am just normal. Not manic.

I'm taking a couple of weeks to decide. I'm looking for advice from others who've taken them. Did they help and what were the side effects like? I'm already on ADs. They don't seem to work.

OP posts:
MarmadukeM · 21/11/2025 21:14

I take quetiapine, have been taking it for 15 years. I know it can be used to augment antidepressant therapy - I was prescribed it for hypomania when my son was a baby and I reacted to antidepressants by switching into elevated mood. My experience is that they did help me with calming me and quieting my thoughts. I put a bit of weight on but nothing too bad I take 350mg now and I have a full time job etc and manage ok. I will say that it has not prevented me from going into depressive episodes when I’ve encountered a lot of stress but I definitely would have been a lot worse without them.
don’t be scared to try them - if they don’t agree with you you can always come back off them. They might be ready good for you xxx

Crazyasfuck · 21/11/2025 21:17

I took low dose Quetiapine with my AD for a while. It was great for sleep but didn’t do much for my low mood at that low dose. I stopped taking it as I hate medication

PennyJenny77 · 21/11/2025 21:23

Thank you both. What were you like initially, when you first started them? That's the bit I'm nervous about. ADs definitely made me worse at first.

OP posts:
Crazyasfuck · 21/11/2025 21:35

The good thing about Quetiapine is that it starts working pretty much straight away. I went from sleeping a couple of hours a night maximum to being knocked out an hour after taking it.

Ramblingaway · 21/11/2025 21:49

Quetiapine, whilst a useful drug, is not a mood stabiliser, it's an antipsychotic. Mood stabilisers could mean something like lamotrigine or possibly lithium. It could also be valproate, but they don't usually prescribe that to anybody who could get pregnant. Lamotrigine sent me manic. Lithium I'm trying at the mo but it's a faff with blood tests weekly at the start. You really need to know which exact drug your psych is thinking of to make a decision. Did they specify, if you feel comfortable sharing?

Crazyasfuck · 21/11/2025 21:54

Ramblingaway · 21/11/2025 21:49

Quetiapine, whilst a useful drug, is not a mood stabiliser, it's an antipsychotic. Mood stabilisers could mean something like lamotrigine or possibly lithium. It could also be valproate, but they don't usually prescribe that to anybody who could get pregnant. Lamotrigine sent me manic. Lithium I'm trying at the mo but it's a faff with blood tests weekly at the start. You really need to know which exact drug your psych is thinking of to make a decision. Did they specify, if you feel comfortable sharing?

That’s not correct. Quetiapine is also a mood stabiliser

Ramblingaway · 21/11/2025 21:57

Quetiapine is used as a mood stabiliser, but as a drug class, it's under the antipsychotics. So I'd be surprised for a psychiatrist to be meaning that if they were saying mood stabiliser. But it's possible.

MarmadukeM · 21/11/2025 21:59

I agree with @Crazyasfuck i definitely have it as a mood stabiliser. Texhnically it’s described as an atypical antipsychotic but, for example, the OP is being offered it essentially as an extra boost of antidepressant. I have never been psychotic I was put in it to stop
mood swings/hypomania.
i believe it’s much less likely to cause issues than say lithium which can cause kidney problems etc. I just get bloods and ecg once a year
@PennyJenny77 i was quite sedated for a day or two but quickly got used to it. I started on 50mg x

Crazyasfuck · 21/11/2025 22:00

Ramblingaway · 21/11/2025 21:57

Quetiapine is used as a mood stabiliser, but as a drug class, it's under the antipsychotics. So I'd be surprised for a psychiatrist to be meaning that if they were saying mood stabiliser. But it's possible.

My psychiatrist does. OP is already on ADs and Quetiapine is used in conjunction with ADs for depression.

ThePure · 21/11/2025 22:07

Could equally be lithium or lamotrigine as both are used for antidepressant augmentation (or aripiprazole or lurasidone even)

PennyJenny77 · 21/11/2025 22:07

I definitely need to ask her more questions. I don't know which drug she was thinking of. Also, she's keen for me to start it as an inpatient. I am going to email her secretary tomorrow to find out more.

OP posts:
Fiftyandme · 21/11/2025 22:09

Crazyasfuck · 21/11/2025 21:54

That’s not correct. Quetiapine is also a mood stabiliser

Nope. It’s an a-typical antipsychotic.

Off label uses include sleep aid and mood stabiliser, but it’s not a mood stabiliser

weegiemum · 21/11/2025 22:10

I take risperidone 2mg as a mood stabiliser although, like quetiepine, it’s technically an antipsychotic. I have long term severe depression for which I also take escitalopram and amitryptaline (which is also used by my neurologist as a painkiller - all very complicated!).
I really think I’m going to be on these medications for life, but I’m totally at peace with that - if I was a type1 diabetic I’d be on insulin for life! My brain just doesn’t work perfectly and needs an extra boost to work normally.
With these medications I can hold down part time work and also study for a career change. Without them I’m emotionally labile and unable to live a normal life. My moods don’t stabilise themselves - a simple little tablet twice a day sorts that out!

Ramblingaway · 21/11/2025 22:11

@PennyJenny77 not sure if you've found this site already, but it's got a bit about all the different meds people have mentioned so far.are mood stabilisers? www.mind.org.uk/information-support/drugs-and-treatments/lithium-and-other-mood-stabilisers/about-mood-stabilisers/ Mind page. Wishing you all the best with everything including the admission if needs be xx.

Crazyasfuck · 21/11/2025 22:11

ThePure · 21/11/2025 22:07

Could equally be lithium or lamotrigine as both are used for antidepressant augmentation (or aripiprazole or lurasidone even)

I tried Aripiprazole before Quetiapine. It made me feel really good to start off with but then I had awful side effects (terrible feeling of restlessness and inability to sit still) so I had to stop that.

Ramblingaway · 21/11/2025 22:12

Sorry, I'm rubbish at pasting links, but hopefully that works

Crazyasfuck · 21/11/2025 22:15

PennyJenny77 · 21/11/2025 22:07

I definitely need to ask her more questions. I don't know which drug she was thinking of. Also, she's keen for me to start it as an inpatient. I am going to email her secretary tomorrow to find out more.

Is that private or NHS inpatient treatment OP?

youalright · 21/11/2025 22:17

Im on lamotrigine and its changed my life best drug I've taken

Ramblingaway · 21/11/2025 22:19

youalright · 21/11/2025 22:17

Im on lamotrigine and its changed my life best drug I've taken

I'm so jealous, I really wanted it to work for me, it's got such a short side effect list compared to others. I was gutted when I went up as high as a kite!

PennyJenny77 · 21/11/2025 22:19

Crazyasfuck · 21/11/2025 22:15

Is that private or NHS inpatient treatment OP?

It's private. I'm not sure I can commit as it's 2 weeks at least. I'm hoping I can start it as an out patient instead.

OP posts:
youalright · 21/11/2025 22:22

Ramblingaway · 21/11/2025 22:19

I'm so jealous, I really wanted it to work for me, it's got such a short side effect list compared to others. I was gutted when I went up as high as a kite!

Aww its so frustrating how many drugs we have to go through to get the right one that works for us. When all you want is to feel "normal"

youalright · 21/11/2025 22:23

PennyJenny77 · 21/11/2025 22:19

It's private. I'm not sure I can commit as it's 2 weeks at least. I'm hoping I can start it as an out patient instead.

You absolutely don't have to answer as it's none of my business but if you do feel comfortable how much does that cost?

Crazyasfuck · 21/11/2025 22:24

PennyJenny77 · 21/11/2025 22:19

It's private. I'm not sure I can commit as it's 2 weeks at least. I'm hoping I can start it as an out patient instead.

As it’s private, I’d say to go for it. It will give you time to have a rest and for them to monitor and look after you when you start the new medication.

NHS MH inpatient treatment is a completely different beast (I’ve had both and would never willingly have NHS treatment again)
Good luck xx

Crazyasfuck · 21/11/2025 22:26

youalright · 21/11/2025 22:23

You absolutely don't have to answer as it's none of my business but if you do feel comfortable how much does that cost?

Mine was covered by medical insurance but it was £20k for 28 days inpatient treatment.

youalright · 21/11/2025 22:27

Crazyasfuck · 21/11/2025 22:26

Mine was covered by medical insurance but it was £20k for 28 days inpatient treatment.

Shit thats expensive 😩