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5 new types of diabetes?

7 replies

RueDeWakening · 23/03/2018 10:57

Has anyone seen this research about there being 5 new sub-types of diabetes? DH heard a podcast about it last week (not sure which one) and mentioned it to me.

I've found this, which seems to say they're all sub-types of type 2 rather than type 1, but still interesting (I'm T1):

Cluster 1: Called "severe autoimmune diabetes," this form is similar to type 1 diabetes. People in this cluster were relatively young when they were diagnosed, and they were not overweight. They had an immune system (autoimmune) disease that prevented them from producing insulin.
Cluster 2: Called "severe insulin-deficient diabetes," this form was similar to cluster 1 — people were relatively young at diagnosis and were not overweight. They were also not producing much insulin. But, crucially, their immune system was not the cause of their disease. People in this cluster "looked for all the world like [they had] type 1" diabetes, but they didn't have "autoantibodies" that indicate type 1, Wyne said. Researchers aren't sure why this happens, but people in this group may have a deficiency in the cells that produce insulin.
Cluster 3: Called "severe insulin-resistant diabetes," this form occurred in people who were overweight and had high insulin resistance, meaning their bodies were making insulin, but their cells were not responding to it.
Cluster 4: Called "mild obesity-related diabetes," this form occurred in people who had a milder form of the disease, without as many metabolic problems as those in cluster 3, and they tended to be obese.
Cluster 5: Called "mild age-related diabetes," this form was similar to cluster 4, but the people were older at their age of diagnosis. This was the most common form of diabetes, affecting about 40 percent of people in the study.

OP posts:
justawhisper · 06/04/2018 21:34

I think I'm cluster 2

justawhisper · 06/04/2018 21:35

I did a research thing and they took loads of blood. I make zero insulin but am negative to some anti bodies or something. Have the results somewhere.

RueDeWakening · 06/04/2018 22:15

The c-peptide antibodies (is that what they're called?)? I was diagnosed before that test existed, I was a kid so I was type 1, no arguments!

OP posts:
justawhisper · 06/04/2018 22:55

It says GAD antibodies negative. The c peptide to say how much insulin I Male was def a big fat zero. I was 17 when I got it. Do you have any other auto immune conditions? Currently I haven't

RueDeWakening · 07/04/2018 21:02

I have MS too, diagnosed 10 years ago - have been T1 for 34 years. There's a theory I read about that claims once you have one autoimmune thing you pick up others every 15 years or so! I'm not doing too badly if that's true Grin

OP posts:
WaitingForSunday17 · 08/04/2018 15:02

I'm 25 years in and currently 'only' have the t1 diabetes. My dad is 37 years in and he only has t1 as well...

ArkAtEee · 18/06/2018 21:11

Gosh, I got Crohn's at 17 and T1 diabetes at 32! I'm on immunosuppressants for the Crohn's now so hopefully won't have a nasty shock at 47! Grin

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