APOE4 gene testing

[LovelyBath77]

I have a family history of dementia, so did genetic testing and I have a copy of the APOE4 gene. Feeling quite stressed about it. I wondered if anyone else had done this and what if anything to be done about it. I have looked into the Bredesden book End of Alzheimers but not convinced really and we can't get the testing etc here.

I didn't know you could get a test for it. Was it privately or nhs? Sorry to hear you're going through this.

I have 2 copies! My mother, her mother and her father all had demetia, I'm not sure I should have checked myself out. The advice is that 2 copies add up to some 60% likelyhood of getting it, so there's 40% of not, so not so bad, and much much better for you if you only have one copy, so don't worry. Also, obviously, the same old things - loose weight, excercise, eat healthily, don't smoke, and cut down on complication and stress in your life. Oh and learn another language!

Is this the private test? There is lots of confusion surrounding it from what I've researched. My friend is about to undergo NHS testing - she has been advised that APOE is not particularly useful and can cause more anxiety than anything.

Oh yes, private, quite probably not a reliable test, mine was with 23andMe, DNA ancestry test, you don’t have to look at the medical part... I’m trying to think it might not mean anything.

If you look on the NHS website for genetic testing it specifically mentions that test as being u reliable and causing unnecessary stress x