Have they tweaked it for Omicron? No, that will take about 100 days to do and get to production.
How do they know a booster makes a difference against Omicron? Not sure, but I think lab studies - vaccine versus virus in a test tube, or something like that - backed up by early observation of the vaccine status of people who are proved to have Omicron.
Not hearing of local hospitals being overwhelmed…. It’s only 2.5 weeks since Omicron was identified and a couple of weeks since the first case in this country was identified. And it takes 1-2 weeks after first symptoms before people are ill enough to need hospital care. So, it’s too soon to see hospitals overwhelmed.
But you won’t have to wait long. The doubling time for Omicron is 2-3 days, and we had about 50,000 cases today, and it’s estimated 20% of cases in England now are Omicron. So that’s 10,000 Omicron cases today, 20,000 on Thursday, 40,000 by the weekend, 80,000 by the middle of next week, 160,000 for Christmas, 320,000 the Monday after Christmas, over half a million to see in the New Year. That’s new cases per day.
So something needs to happen to interrupt that exponential growth.