QUESTION about omicron/AZ/boosters efficacy.

[heldinadream]

I’m going to try and be very clear about what I’m asking. So I’ve seen it reported, by the BBC and Sky, not randoms, that the Astra Zeneca vac x2 looks as if it gives 0% protection against omicron after 6 months. I’ve also seen it reported that boosted people are by far the best protected. What I haven’t seen is anyone join up these two pieces of info. So where – if anyone knows yet – does that leave someone who, like me, has had two doses of AZ and then a Pfizer booster?

Am I protected like any other boosted/3 jabbed person, or should I consider myself potentially back at only having had, in effect, one jab? Very grateful if anyone has any insight into this so I can decide whether I’m at more risk than it would seem. Thank you.

No. As I understand regardless of your initial vaccinations, having the mRNA booster gives you 70-75% protection.

A high percentage of people will be in the same position in this country so hopefully someone can come along with some data.

I wondered the same thing

I think the headlines are very misleading & scaremongering (no change there then). Being double jabbed still offers very good protection against serious illness/hospitalisation etc

@titchy

No. As I understand regardless of your initial vaccinations, having the mRNA booster gives you 70-75% protection.

As you understand? Do you have an expertise or are you just doing what I'm doing, hearing and passing on what's reported? I'm after expert opinions on this not just what's already been reported. Do you have a source for 70-75% that's specific to the first doses being AZ?

The data suggests that 2 Astrazeneca plus a booster will give you the pretty good protection. Mixing vaccines also gives a robust response.

Also, the data that AZ isn't protective may well be unreliable (and authors stated as much) as there were so few who had had AZ in the group of different ages.

This was also about symptomatic infection, not protection against death/serious illness.

Your T and B cell protection even after two AZ and no booster may well still be very protective (and there is some evidence that T and B cell protection is better longer term with AZ).

This confused me too, is someone with a 3 phifzers more protected than one with 2 AZ s & 1 phifzer.

I also don't understand the passports thing as people get boosters at different stages so how does that work.

Useful thread here:

mobile.twitter.com/kallmemeg/status/1469351833416122369

"Do you have a source for 70-75% that's specific to the first doses being AZ?"

Yes, it's in this report, the UKHSA VoC Technical Briefing dated 10th Dec. The graphs on page 21 are the results of the testing on AZ and MRNA vaccines.

https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachmentdata/file/1040076/TechnicalBriefing_31.pdf

Have a look at this thread and the post numbered 1.:

twitter.com/kallmemeg/status/1469350830864322560

Ooops just saw it's already been posted :).

https://www.gov.uk/government/news/covid-19-variants-identified-in-the-uk

I saw this on Twitter but from the Daily Fail (sorry). It says 2 AZ boosted by Pfizer gives 71% protection against infection with omicron compared with 76% from 3 Pfizers.

[quote Grimbelina]Useful thread here:

mobile.twitter.com/kallmemeg/status/1469351833416122369[/quote]
Thank you that's EXACTLY what I'm looking for. I'm not a scientist at all and mostly do not know how to interpret scientific stuff but I know expertise when I see it (hopefully!) and that looks like the real deal and reassuring.

2 Az and a Pfizer are good.

On the 2 Az offering zero protection I think that’s misleading. There isn’t enough info yet - I believe because the figures are mostly coming from South Africa where nobody had Az.

Thanks to you all I feel I've been answered as far as is possible and I feel greatly reassured.
I hope other people with that combo of vaxxes are similarly reassured.

Top stuff!

Also it's in important to note that they're saying that while two AZ jabs without a booster might not stop you from contracting the omicron variant. It should still protect against hospitalisation and death effectively.

Is it the third jab or a recent booster that's the key? My 15 year old has had 2 Pfizer jabs but I'm unclear whether that's effective now or not.

What about 2 AZ and Moderna booster?

@Papyrus

Also it's in important to note that they're saying that while two AZ jabs without a booster might not stop you from contracting the omicron variant. It should still protect against hospitalisation and death effectively.

That's what I'm aiming for. I fully accept that sooner or later I'll probably get covid, and that now it'll probably be omicron. I just want to be protected from it being serious as far as is possible. I'm all up for all the jabs!

I've had AZ, Moderna, Moderna but I'm assuming that is good too!

@Claudethecat that's what I've had and I'm wondering too

@Claudethecat

What about 2 AZ and Moderna booster?

Only Pfizer and Moderna are being offered as boosters. Both are MRNA vaccines, both give good efficacy as boosters regardless of which type vaccine you had previously.

That's not what she's asking, she's asking if there is data for 2AZ plus Moderna.

I thought i saw on the news yday (itv) that
2 x AZ = 30% protection
2 x AZ plus Pfizer booster =70% protection
2 x Pfizer plus Pfizer booster = 75% protection

I dont have a link but thats what I remember from the news (but maybe I wasn't paying attention)