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Does Az run out

16 replies

Rizzoli123 · 05/12/2021 16:50

Husband has read an article saying az runs out after 6 months and has no protection. Is that right?

Is pz the same

OP posts:
PinkSparklyPussyCat · 05/12/2021 16:54

Where did he read this 'article'? I'm no scientist but as far as I'm aware (thanks to Google) protection wanes after 5 to 6 months so we have less protection but doesn't disappear completely. The same is true for Pfizer.

IgneousRock · 05/12/2021 16:54

It doesn't run out completely so you have no protection, but the effectiveness drops gradually over time. That applies to all Covid vaccines.

IAmHereForTheFood · 05/12/2021 16:58

It’s not just antibodies that matter

Memory B cells, which can rapidly deploy more antibodies in the event of re-exposure to the virus, tend to stick around, and so do T cells, which can attack already-infected cells. Both provide an added measure of protection should SARS-CoV-2 sneak past the body’s first line of defence

Tommika · 05/12/2021 17:00

@Rizzoli123

Husband has read an article saying az runs out after 6 months and has no protection. Is that right?

Is pz the same

It’s not right The effectiveness drops, but it doesn’t have zero effect

Hence the recommendation for boosters

ErrolTheDragon · 05/12/2021 17:02

No, he's wrong.
If anything, the AZ seems to give longer term protection via the memory T cell mechanism than the other types of vaccine.

amicissimma · 05/12/2021 17:04

Antibody levels following vaccination and infection are thought to decline over time. This is natural and occurs with responses to all pathogens. They don't just fall off a cliff so that one day a person has antibodies and the next not. It also depends on a person's own immune system, how it reacted to the first and second exposure, how its antibody levels hold up in general, how much an individual uses current antibodies to fight infection and how much T and B cell responses, etc.

A decline also occurs in antibody levels of people who received the mRNA vaccines. Although it is generally thought that on average they originally made higher levels of antibodies on receiving the vaccine. I'm unaware of any studies where the participants were carefully controlled for other factors such as age, general health, strength of immune response in general and so on.

Immunity also depends on other factors such as T and B cell responses, which may be greater or lesser after mRNA or AZ vaccines. It's quite possible that the difference in immunity over time between different individuals is greater than the difference between vaccine received.

A sample of one is not much use, but I paid for antibody tests shortly after my second vaccine (AZ) and after 6 months, just before my booster. I can't find information about what are 'good' levels, but, although they had reduced, I still had enough antibodies after 6 months to reassure me.

Christmas3143 · 05/12/2021 17:25

I had Az over 6 months ago and this makes me anxious too. Was meant to have booster this evening but I've had to pcr this morning due to tickly cough and dp is ill after being w close contact so both of us waiting for test results!! I have re booked but much later in the month due to lack of appointments. If what we have turns out not to be covid (hopefully it isn't of course) I worry about the protection I will have at Christmas without the booster. Dp's second vaccination was only 4 months ago and Pfizer!

gsaoej · 05/12/2021 17:26

Absolutely, my db went into intensive care this week with 2xAZ 6 months old. He's out of ICU now.

Christmas3143 · 05/12/2021 17:32

@gsaoej

Absolutely, my db went into intensive care this week with 2xAZ 6 months old. He's out of ICU now.
Omg 🤯🤯 hope your db is okay. This really scared me! I'm due booster today but as above had to cancel! Was hoping booster would be in my system for a couple weeks before Christmas!
TerraNovaTwo · 05/12/2021 17:52

Most vaccines are effective for life or at least your youth - like the ones you have as a baby and toddler. The Covid jab, like the flu jab, have a half life and are for a specific strain. So in reality, these 'vaccines' are more like a medication.

I won't be getting my booster jab as I've had the delta strain and after that was double jabbed. Seems pointless

TerraNovaTwo · 05/12/2021 17:53

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Neversaygoodbye · 05/12/2021 17:59

Both DH and I had 2x AZ, just about to book boosters and I caught covid from DS. DH remained negative and symptom free.

ErrolTheDragon · 05/12/2021 18:11

@TerraNovaTwo

And don't forget the AZ jab is medication originally created for chimpanzees/from chimp DNA.
They weren't. They were created, for human use, using modified chimpanzee adenovirus as a vector. Hmm
JanglyBeads · 05/12/2021 18:18

It doesn’t “run out” but stops working so well, that’s why we all need to get second doses and or boosters.

This is really, really important at the moment because of the high number of cases in the UK AND because of the new omicron variant which may spread much more quickly than previous variants.

JanglyBeads · 05/12/2021 18:19

@TerraNovaTwo

And don't forget the AZ jab is medication originally created for chimpanzees/from chimp DNA.
Am reporting this. Dangerous misinformation.
Willyoujustbequiet · 05/12/2021 19:47

I caught covid 5 months after AZ. Very poorly but avoided hospital.

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