Under 40s booster after AZ

choirmumoftwo · 04/12/2021 20:25

DD (19) had AZ then Pfizer as a third primary dose (immunosuppressive). Felt a bit ropey after AZ but no issues at all with Pfizer.

choirmumoftwo · 04/12/2021 20:26

No heart or blood pressure issues though.

Whatelsecouldibecalled · 04/12/2021 20:29

Following with untreated as AZ wiped me out for a good three days both times. Felt very ill. I'm 33

HarrietM87 · 04/12/2021 20:32

I had the first dose of AZ and was hospitalised with side effects, though thankfully they passed after about 4 weeks (crippling head and neck aches were the thing that lasted, but had fever and nausea etc too). As a result I didn’t have my second AZ dose and got Pfizer 5 months later. I had a night of fever and chills again, but fine the next day.

HarrietM87 · 04/12/2021 20:32

Oh and I’m 34 - only got AZ as my GP had surplus. It was pulled for people in their 30s a week later.

Rade · 04/12/2021 23:03

DS23 had 2 AZ before it was pulled for young people. Then Pfizer booster. He was unwell for 12 hours after the first AZ but nothing for the others.

CovidCorvid · 04/12/2021 23:08

Dd is 20yo and had 2x AZ already, she’s in group 6 and is overdue her booster….she could have booked it a while ago. However she wants AZ again and won’t have Pzifer. She’s worried she won get AZ as now it’s pulled for her age group so won’t book the booster. 🤷‍♀️

Original poster

containsnuts · 05/12/2021 09:20

Thanks for all the replies. It's also compicated by the fact that everyone has had their vaccines at different intervals. The earliest recipients had their 2nd dose at 3 weeks, I had my 2nd dose at the 12 week interval where people after me had theirs at 8 weeks. It's very hard to find info pertaining to our individual set of circumstances.

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InCahootswithOrwell · 05/12/2021 09:28

@CovidCorvid

Dd is 20yo and had 2x AZ already, she’s in group 6 and is overdue her booster….she could have booked it a while ago. However she wants AZ again and won’t have Pzifer. She’s worried she won get AZ as now it’s pulled for her age group so won’t book the booster. 🤷‍♀️

They aren’t boosting with AZ except in exceptional circumstances so her booster will definitely be one of the mRNA vaccines.

Yorkshirepudding1987 · 05/12/2021 09:39

I am 34. I had first AZ In Feb and the second AZ in May. I had my booster on Friday - Moderna.

I didnt have side effects with either AZ, I was very tired yesterday and have a bit of a sore arm but don't feel too terrible.

Rade · 05/12/2021 10:14

@containsnuts

Thanks for all the replies. It's also compicated by the fact that everyone has had their vaccines at different intervals. The earliest recipients had their 2nd dose at 3 weeks, I had my 2nd dose at the 12 week interval where people after me had theirs at 8 weeks. It's very hard to find info pertaining to our individual set of circumstances.

DS had a 12 week gap. AZ, AZ then 6 months gap and pfizer. No side effects from booster.

Original poster

containsnuts · 05/12/2021 10:23

@rade

That's reassuring - thank you.

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Rainbowsandstorms · 05/12/2021 10:59

As it’s a different booster I imagine the fact that you reacted badly to AZ shouldn’t influence how you respond to an mRNA booster. In current circumstances boosters seem to be increasingly important and we know that AZ wains faster than the mRNA vaccines and is potentially less effective than the mRNA vaccines against variants. Though I understand your concerns.

Anyone on this thread who is under 40 and had 2 x AZ how have things worked re your booster? I’m in my 30s and had AZ just before it was pulled for my age group. I’m no longer in a priority group and I’m 5.5 months past my second dose (which I delayed by a few weeks) I’m feeling increasingly worried with all the talk about boosters being so important and knowing that the protection provided by AZ isn’t as strong as if I’d had an mRNA vaccine and I know I won’t qualify for a booster for a little while yet. Is anyone else in similar circumstances?

Original poster

containsnuts · 05/12/2021 12:58

What's missing is a proper break down of risk vs benefits by age and vaccine type. At the beginning of the roll-out we were shown graphics at the briefings that helped visualise where the balance lay for each of us. My understanding is that 2xAZ 6+ months ago should still provide a good level of protection against hospitalisation and death unless you're 80 years old or have a compromised immune system. Some (including the makers of AZ and the WHO) suggest a booster may be unnecessary for most people and would be better given to vulnerable unvaxed people around the world. Moderna have been the first to claim that their vaccine will be less effective against Omicron so with all this do the risks continue to outweigh the benefits?

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Rainbowsandstorms · 05/12/2021 14:50

@containsnuts I agree it would be useful to see a full risk v benefits profile. However there seems to be very little information re how AZ holds up post 6 months. If anyone has any please point me in the right direction, as I’ve not been able to find anything, possibly because most people who had AZ are pre six months or have been booster. However I’m aware that some countries chose to booster individuals who had AZ early which concerns me. I wish the information and risks were clearer but at present I’m keen to get my booster when I can.

Angel2702 · 05/12/2021 15:18

I had AZ with 12 week gap and Pfizer for booster. Sore arm and sore armpit for a few days but that was all.

Original poster

containsnuts · 05/12/2021 15:27

[quote Rainbowsandstorms]@containsnuts I agree it would be useful to see a full risk v benefits profile. However there seems to be very little information re how AZ holds up post 6 months. If anyone has any please point me in the right direction, as I’ve not been able to find anything, possibly because most people who had AZ are pre six months or have been booster. However I’m aware that some countries chose to booster individuals who had AZ early which concerns me. I wish the information and risks were clearer but at present I’m keen to get my booster when I can.[/quote]
This is the most useful graphic I could find - from Prof Spector's Zoe study presentation. It doesn't go beyond 6 months though. Note that this was in reference to protection against infection only. Protection against hospitalisation and death is believed to remain much higher for all vaccine types.

I'm on the bottom right - 2x AZ at 6 months with no prior infection. 71% sounds pretty good to me but I'm no expert.

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Rainbowsandstorms · 05/12/2021 17:57

Thank you, really appreciate you looking this up. Unfortunately I think they are the figures for illness requiring hospital admission. I believe protection against infection with AZ falls to the high 47 percent after 20 weeks / five months which is what concerns me. As I can’t find the figures for six months. The below photo shows the relevant graph. I know I have age on my side but still feel a bit concerned. Not that I want to have endless boosters either.

Here’s the link www.bbc.co.uk/news/health-59260294

gogohm · 05/12/2021 18:02

Dd had AZ in March before it was pulled for youngsters, bad side effects from dose 1 as did I, nothing much from dose 2 and no side effects except a sore arm from moderna booster

Original poster

containsnuts · 05/12/2021 21:31

@rainbowsandstorms.

I watched back over it and he definitely said protection against infection - but of course this is just one point of view. Your graphic is interesting too - thanks for posting. I suppose it just shows that there is not a clear answer.

I'm going for the compromise and putting my booster off a few weeks. I probably will have it eventually, I just want to figure it out a bit first.

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Hearwego · 05/12/2021 21:49

I’m 38 and had the vaccines in the summer , Pfizer. I don’t actually know if it’s worth getting the booster.
I did my bit and wasn’t all that happy about it- now I’m not sure I want to keep having it for the foreseeable future.
I might have it and then call it a day after that.

MrsM36 · 05/12/2021 21:58

@containsnuts

Not anti vax just looking to chat. I had AZ just before it was pulled for my age group. I had a pretty rough time with it - heart/blood pressure related side effects. I still have some issues 6 months later. Received my booster appointment but I'm not sure if I should go ahead with an MRNA booster due to the (slightly increased) risk of heart complications. Trying to find info and weight-up the risk/benefit. Seems most of the already 'boosted' are either older or had MRNA previously. Anyone else in my situation? Thanks.

I am under 40 (just) and had two doses of AZ. I just had a slightly fuzzy head the morning after both doses (I wouldn't have called it a headache as such). I had my MRNA booster yesterday morning and so far the only notable thing is that my arm is definitely more sore than after either of the AZ injections... it properly feels like it has been repeatedly punched & like there should be a visible bruise (there isn't though).