Vaccine during incubation period or undetected asymptomatic case

[DirtyBlonde]

Does anyone know if the vaccine is still properly effective?

I know you mustn't get it if in isolation (positive, or awaiting results) but is that just to protect staff at the centre, and upholding the general rule of not giving any vaccines if the person has a fever, or does it compromise the effectiveness of the vaccine?

There must be people who have received their vaccine and then started covid symptoms shortly afterwards, so likely incubating at time of vaccination, or who didn't even know they had it until a routine LFT showed positive. Are they still getting full benefit of the jab?

No they won’t get the full benefit of the first jab as it takes 21 days to begin to work, so if they were to have covid on or around the date of vaccination, the vaccine wouldn’t particularly help.

Thank you, but that's not quite what I meant

I know it will be too early to affect the course of an infection acquired around the time of the jab.

What I want to know is if you have covid at the time of your jab, will your body still form a typical level of response the the jab or might it be lessened (or perhaps augmented) because the wild virus is there at the same time? Going forward, will it still offer the expected vaccine level of protection against second and subsequent infection?

Yes, vaccine will offer protection going forward, don’t know about level of response though.

Do you have a source for that?

I'd really like to know about the level of response, and whether it differs significantly from someone who was not incubating/in midst of asymptomatic infection. Google isn't really helping, but if your source has references I might be able to track something down that way

Hard to say, I should think, as how would you know what immunity came from the jab and what from the infection itself?

Tests can detect the difference between vaccine and disease acquired immunity.

Now, it's possible that no-one has really looked in to this - again does anyone know?

Or perhaps there's a good parallel with a different disease?