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Original poster

Need advice on vaccine when pregnant

43 replies

Disabrie22 · 24/08/2021 22:37

Have an underlying heart condition and I’m in the third trimester. This is classed as a high risk pregnancy due to age and intense fertility treatment to get there. It is my first child.
My sister has the same condition and experienced extreme side effects to the vaccine and has been blue lighted to hospital twice. They took a couple of months to recover. We have a close family of very prem babies.
I am worried the vacccine will bring on Labour - what would you do?

OP posts:
MrsSkylerWhite · 24/08/2021 22:38

Talk to a health professional, not unqualified people on a forum.

All the best .

SmidgenofaPigeon · 24/08/2021 22:39

What has your consultant advised?

messybun101 · 24/08/2021 22:40

New helpline from Pregnant then Screwed about the vaccine and pregnancy www.mumsnet.com/Talk/coronavirus/4330401-New-helpline-from-Pregnant-then-Screwed-about-the-vaccine-and-pregnancy

leafyygreens · 24/08/2021 23:22

@Disabrie22

Have an underlying heart condition and I’m in the third trimester. This is classed as a high risk pregnancy due to age and intense fertility treatment to get there. It is my first child. My sister has the same condition and experienced extreme side effects to the vaccine and has been blue lighted to hospital twice. They took a couple of months to recover. We have a close family of very prem babies. I am worried the vacccine will bring on Labour - what would you do?
I would speak to your cardiologist or other consultant about this Flowers Have they not already recommended/advised against the vaccine?

The is no evidence that the vaccines trigger early labour but your situation is very medically complex, and so no-one can really advise you (or should try!) and I don't think the standard resources are going to be very helpful as they are very general.

orangejumpsuit · 24/08/2021 23:28

As above. Talk to your medical team. You simply cannot take advice from strangers on an Internet forum.

Original poster
Disabrie22 · 24/08/2021 23:44

We are a somewhat medical family (retired) and no one can quite decide because the genetic condition we have is rare - and myself and my siblings were diagnosed in our twenties (previously given incorrect diagnosis) due to lack of awareness/medical knowledge. Sadly we are the ones often educating medical practitioners and in many situations have had to take steps to save our own lives. That’s why there’s little trust there.

OP posts:
Original poster
Disabrie22 · 24/08/2021 23:47

I’m talking to you as I was hoping some one might have had the vaccine and given birth - or had advice relating to their medical condition?
All three of us were born prematurely, my sisters children were all born prematurely too.

OP posts:
leafyygreens · 24/08/2021 23:55

@Disabrie22

I’m talking to you as I was hoping some one might have had the vaccine and given birth - or had advice relating to their medical condition? All three of us were born prematurely, my sisters children were all born prematurely too.
Advice would vary depending on the specific medical condition you have though? Most pregnant women with specific complex medical situations will be advised by their teams on the risks/benefit profile and this would be done on a case by case basis.

In general, the vaccines are recommended in pregnancy as COVID can be risky particularly in the third trimester, and is associated with stillbirth. However, the benefits may not outweigh the risks in your specific situation, and I can understand your concern if your sister has the same genetic condition and reacted badly to the vaccine.

I completely understand doctors not being great if it's something very rare, but presumably you're under the care of a cardiologist who would be able to offer some kind of advice? Are there any specialists/research groups looking into your condition? Or specific patient forums?

SmidgenofaPigeon · 25/08/2021 00:24

You must be under some sort of cardiac care if you have a diagnosis? Surely they’ll have advised you.

Original poster
Disabrie22 · 29/08/2021 00:10

They have advised to take it but I have asked if can have Pfizer instead of AZ which my sister had and they have refused.

OP posts:
saltedcaramel87 · 29/08/2021 00:13

@Disabrie22

They have advised to take it but I have asked if can have Pfizer instead of AZ which my sister had and they have refused.
where do you live OP?
Original poster
Disabrie22 · 29/08/2021 00:13

Sadly there is no advice given as they just don’t have the awareness. As I said, it’s rare.

OP posts:
Valhalla17 · 29/08/2021 00:16

I really wouldn't risk it. Know someone who had AZ and it triggered a heart attack + a severe autoimmune disorder. Wait until afterwards, but clearly I'm not a medical professional...

THATmamaofMANY · 29/08/2021 00:19

I had my first pfizer at 34 weeks. Baby is now nearly 2 months old and healthy, born at term with no issues.

ZednotZee · 29/08/2021 00:21

What is your blood type OP?
Are you obese?
How old are you?
Can you shield in any way until your due date?

saltedcaramel87 · 29/08/2021 00:27

@Disabrie22

Sadly there is no advice given as they just don’t have the awareness. As I said, it’s rare.
But you said they've advised you to have it? I am confused that they have said you must have AZ - so you're not based in the UK?

There is no indication that blood type is predictive of COVID severity, beyond that fact it's associated with ethnicity, and personally don't think anyone should be advising OP especially given no knowledge of her complex medical history (she hasn't even named the genetic disorder she has!)

ZednotZee · 29/08/2021 00:30

Plenty of studies which purport blood type to be indicative of both susceptibility and severity.

Quick Google scholar search should avail you of the current research.

saltedcaramel87 · 29/08/2021 00:33

[quote ZednotZee]www.infectiousdiseaseadvisor.com/home/topics/covid19/o-negative-blood-had-lowest-probability-of-coronavirus-infection-abo-blood-types/[/quote]
@ZednotZee

The studies these claims are based on (including the one in the article) are observational and have methodological limitations which limit how much can be taken from them. They have been widely reported to not be robust evidence of a causal relationship between blood type and COVID severity - if they were they would be included in the risk score calculated for patients. This is not something the OP could use to make a decision on whether she should be vaccinated in pregnancy or not.

As I said, any differences would largely be explained by ethnicity which authors often fail to adjust for.

Totallydefeated · 29/08/2021 00:34

Why have they refused Pfizer?

ZednotZee · 29/08/2021 00:34

OK, if you can't Google give me a second...

GetDownWithTheCygent · 29/08/2021 00:34

You need to do what you feel is right. I am 21 weeks pregnant and personally have not had the vaccine. I don't think there is enough research on it yet. Nobody knows the effects it may or may not have on the child now or later in life. I have a thyroid condition and in my last pregnancy had to be induced to avoid complications. I still feel that the vaccine is too risky. This is my personal opinion and I am by no means qualified. I wish you the best of luck and hope whatever you decide works out for you

ZednotZee · 29/08/2021 00:40

As I said, any differences would largely be explained by ethnicity which authors often fail to adjust

Hardly surprising in the case of rhesus negativity as this is predominantly found within Caucasian populations.

Still according to the studies appears to be an independently protective factor, especially in the case of concurrent O type status.

saltedcaramel87 · 29/08/2021 00:40

[quote ZednotZee]www.acpjournals.org/doi/full/10.7326/M20-4511

www.ncbi.nlm.nih.gov/pmc/articles/PMC7276013/

link.springer.com/article/10.1007/s00277-020-04169-1[/quote]
@ZednotZee

See my previous post.

Presumably you haven't taken the 3-4 hours needed to read each paper, assess the methods and results, assess for risk of bias etc etc? Did any of them adjust for ethnicity by design or statistically? Epidemiologists have reviewed them, and explained they cannot be used to demonstrate a causal relationship between blood type and COVID severity.

As I said, The studies these claims are based on (including the one in the article) are observational and have methodological limitations which limit how much can be taken from them. They have been widely reported to not be robust evidence of a causal relationship between blood type and COVID severity - if they were then blood type would be included in the risk score calculated for patients. This is not something the OP could use to make a decision on whether she should be vaccinated in pregnancy or not.

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