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Covid

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Potential nasal spray Covid vaccine (animal trial results)

5 replies

CrunchyCarrot · 21/07/2021 08:11

I'm sure my fellow needle-phobes will agree this would be a wonderful development! This seems to be a promising line of research.

In a new study assessing the potential of a single-dose, intranasal COVID-19 vaccine, a team from the University of Iowa and the University of Georgia found that the vaccine fully protects mice against lethal COVID-19 infection. The vaccine also blocks animal-to-animal transmission of the virus.

The vaccine used in the study only requires a single dose and it may be stored at normal refrigerator temperatures for up to at least three months. Because it is given intranasally, the vaccine may also be easier to administer, especially for those who have a fear of needles.

The experimental vaccine uses a harmless parainfluenza virus 5 (PIV5) to deliver the SARS-CoV-2 spike protein into cells where it prompts an immune response that protects against COVID-19 infection. PIV5 is related to common cold viruses and easily infects different mammals, including humans, without causing significant disease. The research team has previously shown that this vaccine platform can completely protect experimental animals from another dangerous coronavirus disease called Middle Eastern Respiratory Syndrome (MERS).

www.news-medical.net/news/20210708/Intranasal-COVID-19-vaccine-protects-animals-against-lethal-COVID-19-infection.aspx

Research paper:

advances.sciencemag.org/content/7/27/eabi5246

Obviously human trials have to be done next, but it's a good start!

OP posts:
XenoBitch · 21/07/2021 12:39

Will be many months before it becomes available though.

CrunchyCarrot · 21/07/2021 14:13

It will. But still, a good development, particularly for people in poorer countries who still don't seem to be getting any vaccines.

OP posts:
Arsebucket · 21/07/2021 15:06

Yeah, I was contacted a couple of months ago to take part in the trial by Imperial College.

CrunchyCarrot · 21/07/2021 16:48

@Arsebucket

Yeah, I was contacted a couple of months ago to take part in the trial by Imperial College.
Was that the same one, @Arsebucket? There are several nasal sprays being researched. I believe this one is starting human trials next week.
OP posts:
Arsebucket · 21/07/2021 16:55

@CrunchyCarrot no idea, i was just sent an email from Imperial college asking if i wanted to take part. I didn’t, so didn’t get further details.

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