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Hybrid Immunity

7 replies

CrunchyCarrot · 29/06/2021 09:29

If you have had Covid-19 and also been immunised by one of the vaccines then you will likely have 'hybrid immunity'. This is very good news.

This is an excellent paper on the subject by vaccine scientist, Prof Shane Crotty. He's pretty much my go-to researcher for anything related to SARS-COV-2 as his lab is at the forefront of research.

Excerpts:

Hybrid vigor can occur when different plant lines are bred together and the hybrid is a much stronger plant. Something similar happens when natural immunity is combined with vaccine-generated immunity, resulting in 25 to 100 times higher antibody responses, driven by memory B cells and CD4+ T cells and broader cross-protection from variants.

What happens when previously infected individuals are vaccinated? The observations in several studies, including those by Stamatatos et al. and Reynolds et al., are that an impressive synergy occurs—a 'hybrid vigor immunity' resulting from a combination of natural immunity and vaccine-generated immunity. When natural immunity to SARS-CoV-2 is combined with vaccine-generated immunity, a larger-than-expected immune response arises.

science.sciencemag.org/content/372/6549/1392

OP posts:
moulderingoldlady · 29/06/2021 09:59

good news!Grin

I have had Covid, mildly though and 2 AZ doses. I do have IgG antibodies, I did an Imperial College test that they sent me, do not know the level though, just that they are present. I was starting to relax but then the Delta variant came along, just hope I have protection against that.

CrunchyCarrot · 29/06/2021 10:26

Yes it is good news, and hopefully will mean that combining vaccines will be allowed and recommended.

OP posts:
coronabeers · 29/06/2021 10:35

It's ok news. I haven't had covid.

OliveTree75 · 29/06/2021 13:55

That is interesting OP. We had covid in march and pfizer end of may. We were just chatting about how much protection we might have. Thanks for sharing

SonnetForSpring · 29/06/2021 14:22

Thanks for posting.

BarbarianMum · 29/06/2021 14:57

I've had it twice and I'm double vaccinated so I should be bomb proof at this point. Unfortunately with a lightly shit immune system this is apparently not the case.

TreaslakeandBack · 30/06/2021 17:12

What if you’re vaccinated and then have Covid? I was that way round.

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