If you have already had AZ

[SweetAsANutt]

and under 30 and due your second AZ soon, do we still get the AZ jab?

Sorry if this has been mentioned before. I couldn't find it anywhere.

Because of the recent news just wondering if I'll still get my second dose or will need to wait for something else.

TIA.

From what I've read if you've already had AZ you'll second dose will be the same, no matter what your age.

Oh okay. Thank you.
I did try to find information but couldn't find it .
Thank you so much .

I would ask if the second dose is the same size or double the first dose. In the trials by mistake they discovered a half size first dose worked better. My worry would be if the people have only had half a dose and the second is double that, could it cause more problems including in people older than 30?
www.bbc.co.uk/news/health-55086927

They’re not doing the half-dose-full-dose protocol in the live vaccinations, they’re doing two full doses.

They are both the same dose size @CassandraKnew, the half dose was an error in one of their trials which seemed to produce slightly better results but wasn't significant enough to alter the way they give the vaccine now.

We are meant to get our second one in this instance, but I don't know if I feel comfortable having it. Thankfully I've got until May though to decide.

@FourWordsImMuNiTy

They’re not doing the half-dose-full-dose protocol in the live vaccinations, they’re doing two full doses.

Strange that they went for the lower efficacy then and risked worse adverse reactions on a first full dose jab. Obviously the people who had problems would have preferred they only had half a dose now.

19yo DD got her 2nd one yesterday.
No pre-existing conditions, btw, she had opportunistic 1st dose in January so was due now.
She says her friends who got 2nd dose recently (same personal health circumstances) found the 2nd one caused fewer symptoms.
She's not crawled out of bed yet (normal for age 19 at 8:30am) but I'll update later if she says she feels unwell.

Strange that they went for the lower efficacy then and risked worse adverse reactions on a first full dose jab. Obviously the people who had problems would have preferred they only had half a dose now.

As a pp said, it wasn’t a big enough sample size to know if the results were statistically significant though. You can’t change the way you administer a medicine to millions of people based on limited data.

Apparently some guy (Prof Anthony Harnden, the deputy chair of the Joint Committee on Vaccination and Immunisation (JCVI) in the UK) was on TV this morning saying every fatal case had been after the 1st jab, with none after the 2nd jab. That seems kinda important to shout out surely?

I guess if your body's going to react in that way it won't wait for the 2nd jab to do it...

DD22 due 2nd shot early May and will have it, as advised. She works in a hospital.

@CassandraKnew

"Strange that they went for the lower efficacy then and risked worse adverse reactions on a first full dose jab."

Not really, when they reevaluated the data there wasn't sufficient evidence to support the half dose option. It appears the increased protection seen in that trial may actually have come more from an increased length between the two doses rather than the first half dose mistake. I think this has now been replicated in other trials.

www.google.co.uk/amp/s/theconversation.com/amp/astrazeneca-vaccine-delaying-the-second-dose-increases-protection-according-to-new-data-154617

3 of ours have had AZ (all under 25) and as far as I am aware they are getting their second doses on schedule. Dp's dd was given the AZ despite the possible link because she has had allergic reactions to drugs so Pfizer is contraindicated

Personally I found this very reassuring,

twitter.com/alexandersmith/status/1379810003972984833?s=21

@NewLevelsOfTiredness

Apparently some guy (Prof Anthony Harnden, the deputy chair of the Joint Committee on Vaccination and Immunisation (JCVI) in the UK) was on TV this morning saying every fatal case had been after the 1st jab, with none after the 2nd jab. That seems kinda important to shout out surely?

I guess if your body's going to react in that way it won't wait for the 2nd jab to do it...

Obviously what he says it true but I'd be very surprised if he was drawing any conclusions from that as the numbers of under 30s who have had 2nd AZ doses won't be in any way large enough to know if there's any difference. It took millions of first doses to highlight this side effect

A colleague at work says he knows someone who had blood clots.

After the Pfizer jab.

I had my first AZ jab last week and can't wait to have my second. I'm 26.

@NewLevelsOfTiredness surely there isn’t much data on 2nd vaccines yet and this will be built up over the next few months? Only a few weeks ago they were saying there was no link between the rare blood clots but new data has emerged, surely this is possible after more people receive their 2nd shot. Also if platelet levels were reduced after the 1st shot but body was able to cope surely it is possible the 2nd dose could reduce platelets further in turn causing more significant problems?

If you've not had a reaction from your first dose you will be fine for your second. It is the first dose that people react to.

@Twinkie01

If you've not had a reaction from your first dose you will be fine for your second. It is the first dose that people react to.

That's a very bold statement @Twinkie01 can you link the scientific porrf please

Just sat and listened to the experts on BBC Breakfast. I'm sure they would have fact checked what information they were giving out via the national broadcaster to the general public. Log on to iPlayer and give it a listen maybe.

Sorry reply to AllThatFancyPaintsAsFair.

They said in the press briefing yesterday that there hadn’t been enough second doses to draw any conclusions yet. I believe they have given about 800000 second doses so far and as of yet they haven’t seen any clots after them but they are monitoring this.

[quote Daisydoor12]@NewLevelsOfTiredness surely there isn’t much data on 2nd vaccines yet and this will be built up over the next few months? Only a few weeks ago they were saying there was no link between the rare blood clots but new data has emerged, surely this is possible after more people receive their 2nd shot. Also if platelet levels were reduced after the 1st shot but body was able to cope surely it is possible the 2nd dose could reduce platelets further in turn causing more significant problems?[/quote]
A fair point and I agree which is why I guess it was a comment on breakfast TV rather than an official public announcement.

I'd just be reassured if I was waiting on a 2nd jab.

I am simply not educated enough in the science to comment on the platelets.

Thank you all for the replies, much appreciated! .

@ThatsShitTryHarder

Strange that they went for the lower efficacy then and risked worse adverse reactions on a first full dose jab. Obviously the people who had problems would have preferred they only had half a dose now.

As a pp said, it wasn’t a big enough sample size to know if the results were statistically significant though. You can’t change the way you administer a medicine to millions of people based on limited data.

However that's exactly what they did when the trial was given approval for 2 doses 3 weeks apart and then they extended the gap to 12 weeks.

Also they are currently doing tests on only 820 people to decide if it's safe to mix vaccines.

Re Professor Harnden he should know a lot about the Oxford Astra Zeneca vaccine because as well as being deputy chairman of the JVCI (Anthony Pollard who developed the vaccine is chairman), he is also at Oxford University's St Hughs college.