There's so many mixed messages about the effectiveness of the vaccine with this variant that I'm finding it hard to feel positive.
Vaccines give your immune system a head start in dealing with the virus - you still get infected, but are able to deal with the infection much faster.
Think about it like a car trying to break to avoid crashing into a pedestrian. If the car is doing 20 mph when the driver hits the brakes, the car stops just in time. This is like where vaccines are so good they stop people from testing +ve for the virus.
Now imagine same scenario, but the car is doing 21 mph. The car needs a little longer to stop and ends up just touching the pedestrian. This is where the immune response is a little slower and you DO test +ve - but the pedestrian in both cases is unharmed!
A lot of attention has focused on how the SA variant is only 10% effective at stopping infections (they mean +ve tests) - but this is only a small part of the picture. Other evidence seems to show the antibodies generated are effective still.
In short, while it's quite likely that if you got infected with the SA strain, you'd test +ve, the vaccine is still going to work almost as well as against the UK strain, at preventing serious disease/death.