It will be 5 vaccines in the UK soon.. then what?

[notevenat20]

Once we have Oxford, Pfizer, Janssen, Novavax and Moderna which seems likely by Easter, what on Earth is the NHS going to give us? Which would you take?

I’ll happily have any of them. Not fussed which one I get as long as I get one.

I’d take any of them

I’d not be keen on having Janssen tbh.

don't care which one, just get that needle in me asap

I’m in the Novavax trial. I’d have of those except Astra Zeneca and would prefer to stick with Novavax.

All of those except AZ I mean to say

Any thanks

I’d not be keen on having Janssen tbh.

Isn't that complicated by the trial participants in S. Africa many of whom have HIV? I think it was over 70% for those in the US. Also, we really need confidence intervals.

All of those except AZ I mean to say

Why not the Oxford vaccine?

I am wondering about this too. Surely one is going to end up better than the others? When we have the flu jab we have no idea about any of this. I wonder if eventually we will find out one is better and then people who had the others will be angry.

Although Novavax if I could actually choose due to trials on variants

Sounds like they all happily do the main thing - prevent serious illness and deaths.

I wouldn't get too hung up on the specific efficacy numbers as it's not a guarantee of anything on an individual level.

Given the announcement just now on the EU controlling exports, does that mean any of these vaccines suddenly become more likely contenders than others? I'm 50 and not in a vulnerable group, so I'm suppose I'm due to be vaccinated in the summer.

I would take any of them. I am young and healthy so just having the reduced risk of serious illness is fine by me. Don't mind getting Covid if it is the equivalent of a cold and I don't have to worry about ending up in hospital.

I'd take any of them but these newer ones have done trials with the newer variants including the South African one, so could actually be better. Although Pfizer and AZ have good efficacy, they haven't been tested against these variants, so there are def positive aspects to these 2 new ones.

I don't think Novacax is ready until the summer so will probably go to younger people.

I'd get up in the middle of the night and walk barefoot to the hospitalin a snow storm to get any one of them.

Not that I have a great fear of the virus itself. Just that anything that I'm desperate to travel as soon as possible and if vaccines are a condition, then obviously I want that.

@JS87

I don't think Novacax is ready until the summer so will probably go to younger people.

According to this they're hoping for the end of March.

Johnson hails new British-made vaccine after ‘spectacular’ trials

www.thetimes.co.uk/article/novavax-johnson-hails-new-british-made-covid-vaccine-after-spectacular-trials-9z9qsj6mj?shareToken=1f81945531efda8a136815209eb13d57

Any of them would be super.

Not sure how much Pfizer we can expect to be imported from the EU if we don't export our AZ to them. It will stop both ways.

I wonder how they will manage the rapid expansion. Currently it is a bit of a bottleneck with the strict priority list invitations, which hasn't become a huge problem yet because supply of the vaccine has also been a limiting factor.
I think they will have to massively expand the places offering the vaccination and send mass texts rather than relying on the postal service which is struggling in some areas.

Unless the EU export ban disrupts any of the supplies, what this means is that we can get through the adult population quicker - remember they have said the current constraint is availability of vaccines. If we had enough vaccine, maybe we could vaccinate a million people a day, get started with those second doses as well as the lower priority groups, and be done by June.

The different efficacy figures won’t matter, because with the large majority of people having immunity from one or other of them, it will be very difficult for the virus to spread. I’m not saying it will die out, though I wish it would, but cases will be at a low level, and hospitalisations and deaths should be very low indeed.

Then, we will have choices, depending on how things develop.

• if we find some vaccines are more effective against new variants, we could revaccinate people who had had one of the less effective ones

• we could hold some stock for if/when immunity wanes - although presumably they have a shelf life. It would make more sense to offer it to some of the billions of people around the world who haven’t been vaccinated yet, and know that we can manufacture more (we are currently building a massive vaccine manufacturing plant which will be able to produce all we need and more, of several different vaccines)

• if clinical trials show that mixing vaccines is effective, or giving a booster of a different one after an initial course gives additional immunity, we could give people boosters later in the year to increase immunity still further. I’m pretty sure they will be doing trials on this, if they haven’t already started.

Any, and hopefully if there is supply the gap between jabs will go back to the safe 3 weeks.

@Marmite27

I’d not be keen on having Janssen tbh.

But it is 100% in trails against serious illness or hospitalisation.

Reckon you will be ok with no symptoms or just cold/mild flu like ones😉

@JosephineDeBeauharnais

All of those except AZ I mean to say

From an interview with the AZ CEO

Oxford University conducted the so-called Oxford trial in UK and Brazil, and we have data for patients who received the vaccine in one-month interval, 2 or 3 months interval. First of all, we believe that the efficacy of one dose is sufficient: 100 percent protection against severe disease and hospitalisation, and 71-73 percent of efficacy overall. The second dose is needed for long term protection. But you get a better efficiency if you get the 2nd dose later than earlier.

A promise our civil liberties will be given back to us would be nice

Will we get a choice ? I'm not bothered really I just want to be able to get on with life