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Are there trials for the annual flu jab

10 replies

notevenat20 · 22/01/2021 20:07

Looking to the future where we need a new variant of the covid vaccine every year, we clearly don't want to go through the same trial process again that we did this year for the existing covid vaccines. This got me thinking...

After they have chosen which annual flu jab to make every February, are there any trials run at all for it? How does it work?

OP posts:
doireallyneedaname · 22/01/2021 20:13

I don’t think so. It’s the same vaccine, it just had different strains added to it. That’s my understanding anyway.

womaninatightspot · 22/01/2021 20:21

It's educated guesswork they spend ages tracking flu strains around the world and modelling most likely strains and then produce vaccine based on that. Some years they're lucky other years not so much.

notevenat20 · 22/01/2021 20:21

I guess this might mean that new covid vaccines would be similarly easy?

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notevenat20 · 22/01/2021 20:23

It's educated guesswork they spend ages tracking flu strains around the world and modelling most likely strains and then produce vaccine based on that. Some years they're lucky other years not so much

Yes. I was just worried about avoiding the hugely expensive and slow phase I,II,III trials.

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WinnieTheW0rm · 22/01/2021 20:24

There got to be some sort of regime.

After all, flu shots have occasionally precipitated Guillame-Barre and narcolepsy, so even using a well proven recipe is surely no guarantee that it's safe and effective.

But presumably it's not the same as one where you start from scratch with a vaccine for a disease for which there has never been a vaccine before

womaninatightspot · 22/01/2021 20:49

I don't think they'd have to redo the trials every time if they're just tweaking for a new strain. That said if the vaccine isn't well matched with the strains that do end up circulating it isn't really effective. The flu vaccine was 10% effective one year. So if they vaccinate us all for the current UK/ original strain in a couple of years and then the dominant strain is a different mutant strain like the one coming out of South Africa there's a decent chance we'll all find ourselves back in lockdown.

I think I'm driving myself to drink ...

Covidasaurus · 22/01/2021 21:17

It’s going to be huge: the whole population will potentially likely need two lots of jabs twice a year. It’s going to be a massive industry going forwards. It’s like the flu programme but x4.

notevenat20 · 22/01/2021 22:09

It’s going to be huge: the whole population will potentially likely need two lots of jabs twice a year. It’s going to be a massive industry going forwards. It’s like the flu programme but x4.

It might only end up being one jab. The Janssen vaccine is reporting soon and that has one jab as an option and there are trials on the two existing drugs to see if one jab is enough.

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didireallysaythat · 22/01/2021 22:15

The sputnik v vaccine is two doses of different viruses vectors - potentially more effective than two doses of the same vector.

AvocadosBeforeMortgages · 23/01/2021 01:00

Here you go - you can volunteer to take part, and they pay you flucamp.com/

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