Are there any vaccines with unexpected late side effects?

[oxcat1]

The danger of unexpected late side effects seems a very real fear for people. I was just wondering, are there any vaccines for which side effects have appeared many months or years on?

I hear about the Pandemrix vaccine and GBS. That affected 1 in 500,000, and developed within weeks of the vaccine, so would already be showing if a similar effect was happening with the Covid vaccine.

Just wondering if there is any precedent that gives evidence for these fears?

Info from: www.nhs.uk/news/medication/swine-flu-vaccine-link-to-deadly-nerve-condition/
This study found an found an increase in risk of developing GBS in the four weeks following the H1N1 swine flu vaccination, and the excess risk was observed only among older people.

I am grateful for your understanding. I am not sure any vaccines will work on me - I have a genetic immunodeficiency as well as multiple allergies so rely on immunoglobulin treatment anyway. My doctors are fairly confident I would not do well with Covid - indeed there is an individual plan in place with the hospital already for how best to manage me should I develop Covid.

It is hard. I do understand and I would hate it to be obligatory for people, but i had hoped more would be in favour. So many say they want to 'do their own research', but how can our understanding match that of the scientists?

The problem will be establishing with the vaccine was responsible or another cause. For example, 1 in 4 of us will get cancer. If you get cancer in 10 years time, who is to say, it’s the vaccine or because you are going to get cancer.

I’m sorry you feel uneasy about taking the vaccine OP. I hope that once it’s starts to roll out, people will have more confidence

@Crazycatlady83 I don't feel uneasy at all! I am desperate for it - although not eligible for this one. It is my carers who are uneasy but I have to depend on them to keep me safe. I am trying to get more information to understand why they are not as keen as I am.
Sorry if I wasn't clear.

Oh sorry @oxcat1 it was me not reading the thread properly! I very much hope you get the vaccine as quickly as you can! It must be very very difficult to rely on others, for your health needs and hear their negativity.

@oxcat1

Is it feasible for you to work for now solely with carers who are willing to take the vaccine? It is apparent that some people are keen to be vaccinated (they may be vulnerable themselves, may have a vulnerable relative they want to protect, etc)

Other carers may perhaps change their minds (or not) once more time has passed and more data is available.

Also, it's not known at the moment whether any of the vaccines will prevent transmission, hence vaccinated carers may not be 'protecting' you anyway

@Ellmau

Thalidomide.

Fucks sake.

(A) it wasn’t a vaccine
(B) the problem with thalidomide was literally the opposite of long term effects. I remember reading years ago that there was a specific point in pregnancy that if a pregnant woman took one single dose of thalidomide she could be handed a written guarantee that her child would suffer severe deformities.
(C) it was 60 years ago and because of it we have much more rigorous drug safety.

We have seen other vaccines be tested and withdrawn. This week the trial COVID vaccine from Australian firm CSL and the University of Queensland is no longer being tested. It seemed to work, without health ill effects, but caused false positives on another test, which would be annoying in later life for people who had taken the vaccine. Because of the false positive recipients might be worried that they had a serious illness, HIV, even though they didn’t. It might cause delay for people who did have HIV too, or cause a more expensive test to be used.
They have found these sorts of bad effects in testing. I’m not worried, and frankly I’d take the CSL/IQ vaccine right now.
As it is I’ll wait for roll out of one of the other vaccines.