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Cross immunity is really common, just look at cow pox.

29 replies

Treesofwood · 22/10/2020 22:08

Interesting tweet from Michael Yeadon earlier this week. This guy really know his stuff, used to work with Patrick Vallance. He has been pointing this out, very scientifically, for some time now and this really helped me understand what he is saying. Why do we assume there's no cross immunity? Cowpox was related to small pox and there was cross immunity. Why would Coronaviruses be different? Is it so hard to believe that a significant percentage of us might have already been immune? After all even if you live with zomeine with Covid you are not actually guaranteed to catch it. Infact I've read reports suggesting anywhere between 12 and 50 percent chance of catching it.

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Treesofwood · 22/10/2020 22:16

Thought I might share the link to the tweet. It's really thought provoking twitter.com/MichaelYeadon3/status/1318657038092767233?s=19

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BoobsOnTheMoon · 22/10/2020 22:19

The tweet sounds a bit mad, what with ALL THOSE CAPITALS, but I've seen something before suggesting that young children are less affected by Covid due to their higher exposure to other coronaviruses (ie they're always snotty little buggers).

AgnesNaismith · 22/10/2020 22:22

Hoping the same can be said for the parents of the snotty little buggers too - got to be an upside to being infected with 10 colds every winter by them.

mac12 · 22/10/2020 22:24

The guy is a nut. He complains the only place he can get published is on Toby Young’s website. There’s a reason for that.

BoobsOnTheMoon · 22/10/2020 22:24

As a parent to a very snotty little bugger - I bloody hope so Grin

BoobsOnTheMoon · 22/10/2020 22:25

"Toby Young's website" hahahahaha yes, a last resort if ever I saw one

CoffeeandCroissant · 22/10/2020 22:26

"This guy really know his stuff"

He really doesn't. He tweeted a completely false story about a Welsh hospital the other day and still hasn't deleted or corrected his false claims:
mobile.twitter.com/ArgusICraig/status/1318534847007232000

www.southwalesargus.co.uk/news/18808008.coronavirus-conspiracy-claims-nevill-hall-untrue/?ref=twtrec

Treesofwood · 22/10/2020 22:26

Why is it being denied by Sage though? Why would children be more likely to catch it for every year older that they are?

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FromEden · 22/10/2020 22:34

I thought it was accepted that there is some cross immunity due to previous coronavirus infections? I've definitely read about it before.

Treesofwood · 22/10/2020 22:40

I think it's a theory that is not accepted by Sage or indeed MH.

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Treesofwood · 22/10/2020 22:41

Coffeeandcroissant The hospital. Said their beds are fully utilised, which is a strange way of putting it. Has he responded at all to the tweet above?

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Thatwentbadly · 22/10/2020 22:42

@Treesofwood

Why is it being denied by Sage though? Why would children be more likely to catch it for every year older that they are?
Because children’s immune systems work in a different way to adults.
CoffeeandCroissant · 22/10/2020 22:46

@FromEden

I thought it was accepted that there is some cross immunity due to previous coronavirus infections? I've definitely read about it before.
"The assumption that T-cells primed by common colds offer protection against SARS-CoV-2 is “completely speculative,” said Dr. Crotty... “It’s possible they help. It’s possible they don’t do anything. And it’s possible they are harmful.” mobile.twitter.com/profshanecrotty/status/1310955730011328514

mobile.twitter.com/VirusesImmunity/status/1313555236007686144

Treesofwood · 22/10/2020 22:46

Thatwentbadly When do children become adults. Not in the legal sense.

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Velvian · 22/10/2020 22:47

www.bbc.co.uk/sounds/play/m000mzpr

This was covered on Inside Health, Radio 4 on 29.09.20. Worth a listen.

CoffeeandCroissant · 22/10/2020 22:51

@Treesofwood

Coffeeandcroissant The hospital. Said their beds are fully utilised, which is a strange way of putting it. Has he responded at all to the tweet above?
Michael Yeadon's tweet said: "A hospital in Wales, Nevill Hall in Abergavenny, has 250 beds. 200 beds are empty. The surgeons are bored & pass much time on the nearby golf course. "

"A spokesman for Aneurin Bevan University Health Board said: "Our hospitals are currently incredible busy and we can confirm that the information in this tweet is incorrect.

"Nevill Hall Hospital has 260 beds, which are fully utilised.

"One ward was closed last week for deep cleaning but this has now reopened."

Treesofwood · 22/10/2020 22:53

Coffeeandcroissant This article from. Bmj also calls for further research
www.bmj.com/content/370/bmj.m3563

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Treesofwood · 22/10/2020 22:56

Coffee Fully utilised to me means that there have been people in them. Doesn't mean there are now
People who work for NHS often comment on emptiness of hospitals since lockdown. I am surprised he's left it up. Why wouldn't he remove it if its not true?

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Tangledyarn · 22/10/2020 23:17

There was something on r4 inside science a few weeks ago on their being some level of cross immunity with other coronaviruses, they thought that may be ine reason why children are much less severely affected than adults.

PigletJohn · 22/10/2020 23:47

It's great to hear Cowpox trotted out as if it was typical.

Do you think that this is how Polio, Diptheria, Scarlet Fever, Measles, Chicken Pox, Mumps, German Measles, HPV and Tuberculosis were defeated?

Treesofwood · 23/10/2020 00:59

Pigletjohn defeated in what sense?

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Treesofwood · 23/10/2020 01:00

Velvian Thanks for the link.i will download and have a listen

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ODFOx · 23/10/2020 06:54

Scientific method: have a hypothesis, test it, amend as necessary.
Michael Yeadon: have a hypothesis, don't test it, refuse to amend even if it is proven false, moan that no one in the scientific community takes him seriously any more. He may be wrong. He may be right. He can't be taken seriously as he does not use critical analysis on his own theories and has been tilting at windmills for a while now.

scaevola · 23/10/2020 07:21

Why would children be more likely to catch it for every year older that they are?

Read up on ACE-2. This extract from a letter in The Lancet is as good a shirt form as any;

"The angiotensin­converting enzyme 2 (ACE2) trans­ membrane enzyme is the cellular receptor for SARS­CoV­2.2 Varying ACE2 expression might a ect disease susceptibility and progression. ACE2 expression is highest in children and young people and women, decreases with age, and is lowest in people with diabetes and hypertension. Therefore, lower levels of expression of the viral receptor ACE2 are found in those at the highest risk for progres­ sion of COVID­19 to a severe disease phenotype"

Treesofwood · 23/10/2020 07:55

That's really interesting. You said this was a letter, so is this someone theory, or a reflection on a paper? Do you have a link?

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