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No symptoms on Cyclogest

18 replies

Nervous123 · 30/01/2022 21:27

Hello, I’m 4w3d pregnant after having 2 miscarriages in 6 months. I’ve been put on 2 x injections of Clexane per day and 1200 mg of Cyclogest since 3 weeks pregnant. My HCG has been getting monitored and last test was at 4w0 days and was 442 and had jumped from 87 a couple days prior which I was pleased with. I had some nausea and sore boobs but feel totally fine now…no nausea, tiredness or sore boobs and starting to fear the worst is about to happen again. Has anyone else been on Cyclogest and taken a while for symptoms to really kick in? Don’t think I can handle another miscarriage 😔

OP posts:
ExpatLivingLondon · 02/02/2022 11:33

@Nervous123

Hello, I’m 4w3d pregnant after having 2 miscarriages in 6 months. I’ve been put on 2 x injections of Clexane per day and 1200 mg of Cyclogest since 3 weeks pregnant. My HCG has been getting monitored and last test was at 4w0 days and was 442 and had jumped from 87 a couple days prior which I was pleased with. I had some nausea and sore boobs but feel totally fine now…no nausea, tiredness or sore boobs and starting to fear the worst is about to happen again. Has anyone else been on Cyclogest and taken a while for symptoms to really kick in? Don’t think I can handle another miscarriage 😔
@Nervous123 Hoping it all works out for you. I'm in a similar situation although my pregnancy is via IVF (frozen embryo transfer). I'm currently 6+3 and I'm taking Cyclogest, Clexane, Aspirin along with drugs to support an IVF pregnancy. I don't have any typical pregnancy symptoms atm, unfortunately.

I'm happy to tell you more about my miscarriage stories if you'd like but I don't want to scare you. You're not alone and truly hope all works out for you!

Nervous123 · 04/02/2022 04:47

Thanks so much for your reply and sorry to hear about your miscarriages as well. Feel like you are suddenly thrown into a world you never expected to be in.

Had early scan yesterday and they are concerned where the egg has implanted and said they can’t rule out a cornual pregnancy (rare form of ectopic). Need to go back in a weeks time for another scan to try and get more information. Felt like I was waiting for something to go wrong but never expected this.

Have you got a scan booked in?

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Tandabear · 04/02/2022 20:57

This reply has been deleted

Message withdrawn at poster's request.

ExpatLivingLondon · 08/02/2022 12:30

@Tandabear

Hi *@Nervous123* I’m sorry to hear about your losses and that your scan wasn’t very reassuring. How are you doing? I just came across your post as was googling “cyclogest no pregnancy symptoms”. I’m 5+5 on Clexane because my blood clots in pregnancy and cyclogest because I had spotting early on. Have had 2 MMC also. Strange thing is I had symptoms like you and they went away after I started the cyclogest. I’m trying not to lose my mind but it’s so hard. I really hope you get some good news next week x
@Tandabear and *@Nervous123* Fingers crossed for both of you!

Yes, completely agree this is like existing in some bizarre parallel universe. I'm struggling to carry on with my regular day-to-day with this pending situation.

If it's any hope I recently met with a friend who said she felt nothing at seven weeks, symptoms didn't really kick in until 8-9.

Tandabear · 08/02/2022 13:05

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Message withdrawn at poster's request.

ExpatLivingLondon · 08/02/2022 13:38

@Tandabear

Hi *@ExpatLivingLondon* thanks for your message. I’m an REALLY struggling with getting on day to day too. I have a scan booked at the EPU on Saturday when I’ll be nearly 7 weeks. I’ve never felt less pregnant. Not even tired. I want to be tired and sick! How are you getting on? Are you going to have an early scan? Have you had any cramping on the cyclogest? I’ve had some very localised cramping and also dull aching. My friend who works in fertility said that’s more like changes caused by hormones, but who knows
@Tandabear Darling, I know the feeling. I wake up every day hoping and praying for vomit and nausea.

I'm just at 7 weeks and will have a viability scan soon. Since I started taking the drugs (Blood thinners, Lubion, Estrogen pills and Cyclogest) before the transfer I have some idea of their side effects while not pregnant. I feel a lot of brain fog.
Examples:

  • I leave my phone in a random cabinet
  • If someone sends me an email that requires an ounce of critical thinking it feels overwhelming
  • when I open up a work file I'll find a bunch of mistakes I made the day before, things like that

I know we all occasionally have these experiences in the best of times, but for me, it's now amplified and 24/7. I'm usually a go-getter and love chopping through to-do lists and projects. Now it feels like that fire has been taken away from me and I'm more lethargic. It's not unbearable, but it's not great feeling like a shell of yourself. Also, lethargic + anxious is a sh*t combo.

In terms of more typical pregnancy symptoms, the only thing that's perhaps a bit more noticeable is I need to sleep more. I honestly can't tell if that's because I'm pregnant or have developed some form of depression on these drugs. Otherwise, I normally live for spice and have found myself less interested in firey food. Once again, can't tell if it's legit or if I've just convinced myself I don't want spice so I think I'm pregnant.

In terms of cramping, hardly any at all. I remember three days after the transfer I felt a tiny little cramp, but that was like, three seconds long, while I was power walking, could have been anything.

I absolutely hate this waiting game, it's so tedious. Please know my thoughts are with you, you're absolutely not alone, and I'm hoping you have nothing but a positive outcome. ☺️

letshope · 26/03/2022 11:43

@Nervous123 @ExpatLivingLondon @Tandabear

Hiya all,

I've come across this post and its given me some reassurance that Its not just me feeling this way.

I'm 6weeks 6days today and have been taking cyclogest and asprin since bfp from having 1mc and 1mmc last year.

I havent really had any symptoms at all. I had sore boobs (under the boob) up till around 5 weeks but since then been feeling normal. My anxiety is sky high! Doubting everything and its causing a massive strain on my mental health.

I do have an early scan booked next Thursday at epu to see where we are with the pregnancy. 🤞

Just wanted to ask how you all got on as it seems we are in the same situation. Any information from you 3 would be appreciated on how you got on with your pregnancys? Xxx

#veryanxiousladyhere

Nervous123 · 27/03/2022 07:03

Hi Letshope,

Can 100 per cent sympathise with how you are feeling! I am now 13 weeks pregnant (something I genuinely never thought I would get to say). My symptoms didn’t hit in until 7/8 weeks pregnant and I think this is really normal. A friend of mine who is 2 weeks ahead of me seemed to have the exact same.

Pre warn you as well I would have days where suddenly I would feel fine (panic obv would start) but then 1-2 days later would be back to the nausea. My symptoms have pretty much gone now other than the tiredness.

I’ve had 10 scans already in this pregnacy as the hospital thought I was having a rare form of ectopic to begin with and have had some bleeding in this pregnacy but all has been fine, touch wood, other than alot of stress and back and forth to the hospital! Scans definitely do help with reassurance and I checked multiple times with the sonographers and consultants I was seeing at the hospital if all these scans would have an effect on baby and was assured it was fine to be scanned regularly. Some people just need more monitoring. So be kind to yourself and if you need a scan go.

Hope everything works out for you and please feel free to message anytime you are stressed. That first trimester is really tough and experiencing losses xxx

OP posts:
ExpatLivingLondon · 27/03/2022 12:07

@Nervous123

Hi Letshope,

Can 100 per cent sympathise with how you are feeling! I am now 13 weeks pregnant (something I genuinely never thought I would get to say). My symptoms didn’t hit in until 7/8 weeks pregnant and I think this is really normal. A friend of mine who is 2 weeks ahead of me seemed to have the exact same.

Pre warn you as well I would have days where suddenly I would feel fine (panic obv would start) but then 1-2 days later would be back to the nausea. My symptoms have pretty much gone now other than the tiredness.

I’ve had 10 scans already in this pregnacy as the hospital thought I was having a rare form of ectopic to begin with and have had some bleeding in this pregnacy but all has been fine, touch wood, other than alot of stress and back and forth to the hospital! Scans definitely do help with reassurance and I checked multiple times with the sonographers and consultants I was seeing at the hospital if all these scans would have an effect on baby and was assured it was fine to be scanned regularly. Some people just need more monitoring. So be kind to yourself and if you need a scan go.

Hope everything works out for you and please feel free to message anytime you are stressed. That first trimester is really tough and experiencing losses xxx

@letshope I was somewhat similar to @Nervous123. I'm now 13 weeks and 5 days, still in shock I've made it this far! My pregnancy was an IVF pregnancy. I'm on 75mg of Aspirin and 40mg of Clexane until 36 weeks (due to a genetic mutation my doctor found after my miscarriage that may make my blood slightly prone to clotting), as well as estrogen pills, lubion injections and cyclogest 400mg at night, I started tapering off these at week 12 and stopped at week 13.

My first trimester symptoms were subtle and fleeting, never consistent. It made me so anxious, I assumed my symptoms would be linear and steadily increase throughout the first trimester but that was not the case at all. They varied day to day and I never had more than a touch of very low-grade nausea. One night I would sleep 12 hours, the next night I was back to my usual seven. One day I had food aversions, the next day I wanted something spicy. With my natural pregnancy that ended in miscarriage the first symptom was sore boobs, with the IVF pregnancy I didn't feel any soreness until 8.5 weeks.

The only thing that was consistent was the IVF drugs made me foggy. I noticed this when I started taking them before the embryo transfer. As soon as I started tapering off of them my mental clarity returned almost immediately (tbh, it scared me to see just how quickly drugs can change me).

I found it nearly impossible, but try and not read into symptoms (or lack thereof). The more people I talked to, the more it seems first trimester symptoms truly vary and everyone's experience is unique. I had scans at 7 weeks, 9 weeks and 11 weeks and 5 five days.

Wishing you all the very best in your journey.

letshope · 27/03/2022 17:37

@ExpatLivingLondon @Nervous123

Thank you both so much for your words. It has made me rethink things in a way.

Unfortunately I have started to have a little spotting today. I also stupidly done a clear blue week indicator test which is staying 2-3 weeks when I should be 3+ now with me being 7 weeks today. 😪

Just dont know what to do now if it is another mc... where do I go from here? I live in the UK and feel my epu doesnt realty give support on what I can do next to try and stop this happening?

I had a full blood work up and nothing come back that stood out on it either from my last mc so I'm really clutching at straws... why Is this happening? 😪

ExpatLivingLondon · 27/03/2022 18:50

[quote letshope]**@ExpatLivingLondon* @Nervous123*

Thank you both so much for your words. It has made me rethink things in a way.

Unfortunately I have started to have a little spotting today. I also stupidly done a clear blue week indicator test which is staying 2-3 weeks when I should be 3+ now with me being 7 weeks today. 😪

Just dont know what to do now if it is another mc... where do I go from here? I live in the UK and feel my epu doesnt realty give support on what I can do next to try and stop this happening?

I had a full blood work up and nothing come back that stood out on it either from my last mc so I'm really clutching at straws... why Is this happening? 😪[/quote]
@letshope I'm sorry to hear and hope it's nothing but a touch of spotting. Is working with a private doctor an option for you? I'm sorry your EPU isn't giving you sufficient support. I'm in the UK and can PM you the details of my doctor if you would like. I'm in London.

Hoping for the best for you.

SophieSoSo · 27/03/2022 18:56

Lovely update OP, I’m glad things are going well!

I had a successful pregnancy after being prescribed cyclogest but you never fully relax so you? My little miracle is 6 next week x

Nervous123 · 27/03/2022 18:57

I’m so sorry you are going through this today and I know what this feels like. I had spotting at weeks 5 and 7 in this pregnacy and in both instances my consultant upped my progesterone and stopped my bleeding. I started on 2 x 400mg Cyclogest at 3 weeks and by week 7 I was 4 x 400mg of Cyclogest. I am now gradually reducing these week by week. Everyone is of course different but this method has worked for me so far.

We went privately this time as I was really fighting with the EPU as well during my last miscarriage. Are you getting the Cyclogest from NHS or privately?

OP posts:
letshope · 27/03/2022 19:43

@Nervous123 I've been given the progesterone via a private appointment with a consultant. Epu last time wouldnt do anything because I'd only had 2 losses.
Time will tell now tomorrow how things go. Just have no hope right now 😪

Nervous123 · 27/03/2022 19:56

It’s so frustrating the lack of help offered. Can you get back in touch with your consultant this evening or first thing tomorrow morning? He may advise to up your dose.

I know it’s hard but try not to give up just yet. I felt it was totally over both times I bled but pulled through it with upping the dose. Also maybe book a scan for tomorrow if you can?

I also bled on Friday just past and was examined at the hospital and was told I have a ectropion cervix meaning I was likely to bleed at points going forward in the pregnacy. It’s basically cells coming away and can be caused by hormone changes. There can be lots of reasons for bleeding but obviously having gone through losses our first go to is this is over but just get in touch with your consultant that prescribed you as soon as you can and don’t listen to anyone until you have spoken to him/her.

Have everything crossed for you
Xxxx

OP posts:
Tandabear · 29/03/2022 07:35

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Tandabear · 29/03/2022 07:50

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ExpatLivingLondon · 29/03/2022 10:36

[quote Tandabear]**@ExpatLivingLondon* @Nervous123*
Wonderful news to hear your pregnancies are progressing. Having fewer symptoms in early pregnancy is just a crazy thing for us, it’s great because we don’t feel like total crap, but it does up the anxiety. And it definitely doesn’t help you predict what’s going to happen next! So pleased for you guys x[/quote]
Thank you @Tandabear! I know statistically, it's logical to worry less about miscarriage once you get to 12 weeks and have the harmony test, but I'm still finding it hard to relax! Trying to think positive.

Wishing all the best to everyone. You're not alone in worrying, and as everyone has mentioned here, symptoms or lack thereof aren't always correlated with success or miscarriage. It's tough, as we're conditioned to think that symptoms = something is cooking.

I also find it disappointing that you have to push your GP to get progesterone. I know the NHS go by their guidelines, but I find it scary when doctors push back or are like "well if it's meant to work out, it will work out" rather than proactively do everything possible to help you. Particularly when you see the proactive approach in the private sector.

I use a private doctor, as soon as I got a positive pregnancy test (with no prior miscarriage history) they had me come in ASAP for bloodwork to measure HCG and progesterone. My progesterone was borderline in their view, and they put me on 400mg of Cyclogest that same day as a precaution. Apparently, this initial bloodwork is standard in the public French health system for every pregnancy. I wish the NHS did more in the early stages. I know this likely isn't possible because there's not enough funding and it's not necessary for most pregnancies, but I feel like it could potentially help so many...

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