I was ttc for two years with DS, no pregnancies in that time, monthly cycles that looked normal though but no joy. I have lean PCOS (AMH reading during clomid was 138, so v.v.high), had 5 rounds of clomid which all failed. Was a risk for OHSS. Was referred for IVF, and I was worried about OHSS again because of my high AMH. I wasn’t offered metformin, presumably because I am thin (in hindsight a mistake imo). Whilst waiting for ivf I read some private ivf clinics recommend inofolic to improve oocyte quality (my understanding is that the wrong isomer ratio, with too much d-chiro-inositol, can decrease egg quality, but all the research I’ve read is that the inofolic brand contains the right ratio of isomers and has good quality control so improves egg quality. But that’s why I choose to use inofolic and not generic myo-inositol where I can’t guarantee quality control of isomer ratios). I had a final blood test, and at this point had been taking inofolic for two months, my AMH had reduced to 40 (almost normal range). Third cycle of taking inofolic I was pregnant, with my now 2yr old DS. My understanding is that it can take three months as that’s how long it takes to take new eggs to maturity. Never needed ivf, got pregnant naturally and inofolic was the only change I made, had tried everything dietary already, cutting out alcohol/sugar/dairy etc. I took inofolic all through pregnancy without issue (DS healthy and normal) and I continued to take it as I have found it makes staying a normal slim weight effortless (rather than a lot of effort before).
Just started trying for number two in January. Got pregnant month one of ttc. Ended in mmc at 8 weeks (but I caught Covid at 4 weeks so who knows). Just got bfp again yesterday first cycle after miscarriage completed. This time round ttc has been effortless, versus two years of hell and almost every intervention to get DS, all of which didn’t work, until I took inofolic.
So as far as I can tell, inofolic (and inofolic alpha this time) have been responsible for all three of my pregnancies, and for taking my AMH from astronomical to normal range dramatically in only two months. I think it was basically a miracle cure, and I was extremely sceptical about supplements having tried Vitex before clomid which made me much worse. Cannot say what is right for anyone else, but wanted to start sharing my experience here because inofolic has been such a success for me.