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Buserelin side effects

2 replies

Lucylucy66 · 04/01/2019 00:40

Hiya
I started on buserelin injections on the 10th December and was due to start my next set of injections this week after my scan.
After about a week and a bit, I was so ill from the side effects that we had to stop my cycle. I had severe dizziness that prevented me from standing or sitting up. I was a little headachey aswell but the main issue was the dizziness and the most horrendous depression. I couldn't stop crying and feeling panicky 24/7. After a day in a & e and another day feeling even worse and passing out every time I sat up, I called it quits.
My worry is that I stopped the injections on the 19th December and I still don't feel right. I still feel a bit dizzy, I have a headache nearly constantly and keep feeling a bit sick and nauseous and I am so so desperately tired.
And I feel constantly horrendously panicky 24/7 which isn't like me at all. Just feel every second like I'm going to die.
Would this still be the side effects from the buserelin?
I would have thought the side effects would stop as soon as I stopped the injections and I can't really get an answer from my nurse at the clinic so I'm hoping someone can help and reassure me that this isn't going to last forever 😭
I just don't feel like me at all and I hate it. I've had a couple of glasses of wine in the last week and instead of relaxing me like it normally does, it's done the opposite.
I just don't know what's happening to my body!
Help! Sad

OP posts:
Lucylucy66 · 04/01/2019 00:48

I've also had the most ridiculous thirst since I started the buserelin - it doesn't matter how much I drink, it never quenches it and I've also become completely intolerant of both my husband's and my dogs snoring! Even if it's very light, I just can't bear it!
Is this normal?

OP posts:
CritterTamer · 04/01/2019 09:35

Hi OP

I've only done short protocol IVF, so when I was taking buserelin I was also taking the stim meds which counteract the buserelin and I was lucky enough not to have any nasty side effects. My understanding is that the buserelin shuts down your pituitary gland to prevent it from making hormones naturally, and this is why you get unpleasant side effects. I don't know how long exactly the buserelin effects last, but I was told after our first cycle failed that the drugs could stay in my system and affect my natural cycles for up to 3 months afterwards. I was lucky and just had two cycles where I ovulate slightly later than usual, then was back to normal, and went on to have a successful IVF cycle 3 months after the first. I know that this isn't the case for everyone though and some people have their natural cycles messed up for several months following IVF drugs.

I'm sorry you had to have your cycle cancelled, and that the clinic aren't helping you much now, but I hope that things will get back to normal for you soon. Maybe ask about the possibility of doing a short protocol next time as you should get fewer side effects from the buserelin.

Good luck! x

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