Immune/NK issues - aka Pred Thread no. 22!

[HappyApple05]

Helllooooo dearies

Opening this new thread looking for a light in the tunnel during my journey towards conception. Would be nice to walk along with people in the same journey. To cut my story short, 3 miscarriages and referred to Mr.S, diagnosed with high NK cells and lupus positive, already on levothyroxine. After 2 weeks of staring at the med pack, I have now finally started on Aspirin, Vit D and Pregnacare plus. Awaiting Ovulation to start on Pred protocol.

Miscarriage history:

1. July 2017 - In my 12 week scan, found foetus with no hb (6 weeks foetus size), devastated! Had severe morning sickness, didn't predict anything negative. Took my son (6 years then) to the scan planning to break the surprise where he could see his sibling in scan.. We all broke down, opted d&c

1. March 2018 - started bleeding in 6 weeks and miscarried naturally.

1. July 2018 - spotted in 6 weeks, scan at EPU no pole, returned when 9 weeks along, still nothing, opted d&c

Bought the ovu predictor kit for the first time, counting days to use it. Any of you in the same position? Would be great to hear your stories and cheer each other up towards the destination. Previous threads were beautiful, so supportive but sadly the latest post was in Sep 2017. So most of them would have crossed the bridge. Decided to start on a fresh thread.. So here we are....

Looking forward to catching up... Take care you guys.... Plenty of baby dust to everyone

@DaniMERL & @Megan234
Hey ladies

I just wanted to comeback and check in with you guys! I had to leave MN as I just wanted to have positivity around me and not dwell on what I had been through with my losses - so I'm sorry I disappeared

also I wanted to say I gave birth to my little rainbow girl on 5/5- she's 6.5 weeks now and she's just wonderful!

After three losses Dr S's protocol worked for me! And I couldn't be happier or more grateful

I remember how much hope it gave me when I read success stories on here so wanted to come back and share mine.

I'm also so happy to read that you're pregnant @DaniMERL !!!! Amazing!!!

What's @Megan234 News!!? I couldn't see a recent post from her ?!

Good luck to everyone on this thread
And I hope you all get your rainbow babies

💕

Amazing to hear from you @zarala! Many congrats to you too. I have been thinking of you.
All good here, the scan yesterday went well. DD is 23 Dec! xx

@ zarala - Many congratulations!! Amazing news..remember u and meghan from old threads..

@Zarala I’m so happy for congratulations, baby girl how lovely 💗
@Hopeful07 nice to see you back here, good luck with the treatment 🤞
I’m 12 weeks pregnant and having the nhs scan next week and the following week scan with the prof🤞 This time Mr S added steroids to my treatment as well as Hydroxy. I’m still nervous, but hopefully things will progress in the right direction.
Warm welcome to the new ladies here, Mr S makes dreams come true, don’t give up Xx

@Zarala I’m so happy for you congratulations, baby girl how lovely 💗
@Hopeful07 nice to see you back here, good luck with the treatment 🤞
I’m 12 weeks pregnant and having the nhs scan next week and the following week scan with the prof🤞 This time Mr S added steroids to my treatment as well as Hydroxy. I’m still nervous, but hopefully things will progress in the right direction.
Warm welcome to the new ladies here, Mr S makes dreams come true, don’t give up Xx

Sorry I can't find anywhere how to delete the first post x

@Megan234 oooh! Good luck!! I have all my fingers crossed for a smooth and easy pregnancy for you!!! I'm really happy to see this news !!!

@Hopeful07 thank you very much
Where are you on this journey? Hope all is going well for you!

@Megan234 great news..fingers crossed for u. And i get more confidence that the hydroxy ll do the trick for me too..
@zarala - i ll be having my frozen embryo transfer in 10 days if the scan goes well on monday..Mr.S added hydroxy for me, so bit hopeful..

Wow I didn't check in for a few days and I have missed so much! So lovely to hear from @Nixwix @Sunshineblonde1 @Megan234 with your amazing pregnancy updates, please do keep letting us know how you are getting on. ❤️ @NixWix I can't believe you still don't know! How on earth has he kept that to himself! Does anyone else know?
Great news on your scan with prof A @DaniMERL 😀 And good luck for your scan @Widdendream77 🍀
@Lau2019 I hope today goes as well as these things can, thinking of you I hope MrS can see you soon and tweak your plan.

I am having a shocking week. A huge tree branch fell on our phone line and pulled it down along with our fascia and guttering, have been super stressed all week organising BT and roofers and tree surgeons 😡 I am day 8 pred with no side effects at all. I did start a few days after O so I tested yesterday and got a positive but I tested again today and there's no progression so I'm not holding out much hope. AF would be due tomorrow with my new weird short cycle, or Monday with my normal. As always totally overthinking this and confusing myself. 😕
@KittyKatSmile how are you getting on, how's the holiday, when can you test?!! ❤️
Hello to everyone I have missed! 😚

@Chickjen what's one of the lines here? "A line is a line"?! Sounds like congratulations may be in order. Fingers crossed for no AF today or Monday. Holiday is lovely, just what I needed. Meant to test next Friday, will probably go for Thursday (someone who had the transfer on the same day as me is having blood tests on wed so it doesn't seem ridiculous. It would actually be 16dpo which feels late after months of testing early to ensure you can get those intralipids in). Big love. Great to see you back here x

It's another chemical for me 😥 The good thing to come out of it is DH has finally agreed to do the sperm comet test 👍 But the guy I sit next to at work announced yesterday his wife is having a baby, great timing!😠 I am starting some CBT sessions next week which I'm quite looking forward too 😀 Hope everyone else is doing ok? ❤️

Oh @Chickjen I'm so so sorry. Poor darling, especially with that rubbish you're having to deal with at work. You sound very upbeat. Stay strong lovely.

Big hugs @chickjen so sorry to hear that, will be very interesting to see what the sperm comet reveals. My fiancé had the antioxidants after the comet results and it seems to have done the trick along with Mr S’s suggestion of having a strategic ejaculation before the baby dance xxx

Hi hopeful sorry not been online for a while!
So I’m on day 4 of oestrogen atm. I usually have lining dramas so will see how things go!
I take Gcsf from day 5 of oestrogen (urs is 3?) and yes every 3rd day. Also on the hydroxy pred Clexane etc. Can I ask when you had your intralipids? Are you also on aspirin? Last pregnancy I had ivig with gorgy (which worked) and I’ve decided not to have it this time. I don’t know if this is a huge error!!! But shehata doesn’t often use it and has good results so hoping it’s ok?!
Good luck for ur lining scan!!

Chicjen we had major sperm problems. None there and all rubbish ones! I put my dh on a ridiculous number of antioxidants (I spoke to dietician Mel about it and she was great in recommending what he needed to take) and saw mr Ramsey who put him in tamoxifen which helped increase his numbers (and I got a natural preg which I mc!) but then our ivf cycle gave us some good blasts. Just worth a thought. We also did tried to do fragmentation test and aneuplody but not enough sperm for it

So ladies. I've just got my IVF BFP. Excited but obviously utterly terrified and of course feel slightly weird it's not with my boyfriend as planned. Slightly different protocol with my clinic than previously so I'd already had 2 lots of intralipids pre embryo transfer. 5th time lucky as they say...

Huge congrats @KittyKatSmile!! This is it! Xx

Fantastic xx

@KittyKatSmile wow amazing, congratulations! Keeping my fingers and toes crossed for you that this is it 😍

@Anatrina how you getting on? Have you started the pred now? Did you decide to take from ovulation in the end or from BFP?

I had my follow up appointment with Mr S yesterday and got another 4 months of Pred etc. It was super straight forward, he just wanted to know if I’d had any headaches from the meds (headaches, stomach pains etc.) which I’m lucky that I haven’t. They took my blood pressure and then that was it ☺️ I remembered to mention that I was worried about testing at 11dpo given that I’ve never had a positive that early before and always only after a period like bleed and he said the bleeding was probably the first sign that the pregnancy would end in miscarriage (even though I didn’t know I was pregnant yet) as the levels were so low to be even picked up on a FRER. He said I could take pred for 11 days rather than 10 and test on 12dpo. If I don’t get a positive but my period still doesn’t arrive, test again and then he’s happy for me to start the steroids up again if it’s a positive. It was nice to have a potential reason for my weird bleeding in my 3 pregnancies so far and hopefully next time it’ll be so much more straight forward 🤞🏽 So I’m still feeling positive/optimistic for now, although I suspect if in another 4 months I’m back only getting a repeat prescription without a BFP that’ll probably change haha 🙈

In other news I had my first fertility acupuncture session this week & really enjoyed it. I found the ladies details through the Zita West website as they’ve got a ‘near me’ function for the people they affiliate themselves with ☺️ Booked in again for next Tuesday too. If nothing else I just feel like it gives me some time to relax and get out my head! Oh and we’re also getting a puppy 🐶 We pick him up on Thursday so I’ve no doubt our whole lives are probably going to change.

I hope everyone’s enjoying the sunshine/warmer weather? Driving 6 hours home yesterday from Epsom wasn’t fun in the heat but hoping we will get to enjoy it this weekend ☀️

Hi @wishing5star! You’ve got an excellent mindset this positivity will get you far 😍 and super exciting about the puppy! That’ll keep you pre-occupied whilst you are on this journey. We got two kittens last year after my last miscarriage, I now call them my pregnancy cats 😋 They really helped to have a focus and animals are so intuitive! Your puppy will soon sniff out when your pregnant.

I just wanted to say best of luck for your journey, your doing everything right to support your mind and body by the sounds. I too loved Accupuncture and will be returning back for the last few weeks of pregnancy. I had in up until 12 weeks and it really helped my psychologically and physiologically

Happy Friday All xx

@Cream123 - Had my lining scan and it was bit not to the mark so had to had another scan yesterday and all seems ok now.. so ll be having my transfer on friday the 5th jul. Mr.S has asked me to take G-CSF from 5 days before embryo transfer, so starting g-csf from this sunday. Had my intralipids on monday the 24th as its 10 days before ET as per Mr.S protocol. I couldnt tolerate aspirin so he took me out of it. So i m on clexane, pred, hcq and gcsf..
Yes Mr.S doesnt use ivig often, guess u should be fine without it..
So do u know when ur transfer s going to be?

@KittyKatSmile - congratulations..keeping my fingers crossed for u

@Chickjen - so sorry to hear..hope u get to find something from ur DH's test results and u can take it forward from ther..

@Megan234 - how was ur nhs scan?

Hope everyonelse is doing ok..

@KittyKatSmile that is such great news! 😍 I don't know how you resisted this long 😂 I was tempted to ask yesterday how you got on but I wasn't sure if you would want to share yet. I have EVERYTHING crossed 🍀
Sperm comet is booked! I'm really worried how he'll take it if they find something, I almost hope they don't, but the sadistic in me thinks it's time he shared some of the blame 😄

Congratulations @KittyKatSmile Amazing news! 😊

@Wishing5tar I’m good thank you. Still waiting for ovulation after not trying for two months while waiting to see Mr S. I’m going to stick with the plan and take from ovulation or just a day after. My results appointment was just after ovulation last month so this one has taken a loooong time to come around!

Glad your appointment with Mr S went well and you’ve had some questions answered. Fingers crossed you’ll get your bfp soon! Like @Sunshineblonde1 says you’re attitude is great 😊 Exciting news about the puppy! I have a dog and a cat to keep me busy and a wedding to plan!

Lovely to hear you’re doing so well! @Sunshineblonde1

Fab to hear everyone’s updates xx

@Chickjen I lost track with all the messages above - sorry the hear about the chemical.
How are you doing?
How is everyone else?

Hi hopeful
No first lining scan wed and usually drama with my lining so let’s see. Not long for u till transfer - good luck!