RESPONSE trial thread

[Marchgirl]

For anyone who had joined or is thinking of joining the RESPONSE medical trial for recurrent miscarriage

Gosh you lot ain't half chatty! A lot to catch up on.
So sorry to read about the scans. The waiting just be awful, but a lot can happen in a week and i very much hope that the rescans are perfect and the babies are burrowed in nice and safe.
Glad they're splashing out on the Clearblue pregnancy tests now. I used internet cheapues abd got a FRER to first confirm as I found the budget ones first supplied not sensitive enough.
Regarding flying in pregnancy, the NHS guidelines say that although it's safe to fly in early pregnancy, a lot of women choose to fly after 15 weeks due to the risk miscarriage and morning sickness. And when I spoke to my MW she said it's perfectly safe as there's no link to mc the risk would more likely be deep vein thrombosis, so get done sexy flight socks on to combat that. My flight was only 2.5 hours and I felt alright but wouldn't want to fly any further afield as I'd get angst u that if anything did go wrong I'd feel
a bit too far away from home.
Heading back tomorrow after a really peaceful week in the sun. 14+2 now and wonder if I'll ever stop counting the exact days!
Waves to everyone and hope that this weekend is treating you all well.

Size, glad to hear you had a fab time & sorry didn't send you the restaurant recommendations... Head well and truly in the sand this week!

In terms of flying, I went to Cuba when 6 wks pregnant with dd and as it's been my only successful pregnancy, it certainly didn't do my any harm. Perhaps I should fly this time?

Not sure why but currently feeling very calm about everything. Think it's cause I've got two plans in my head depending what happens on Wednesday.

How's everyone in the 2ww club? Any early signs either way?

hi everyone hope your all enjoying your weekend.....

choccy busy & exciting times ahead........your 20 week scan will be here before you know it. your findong out the sex arent you?

size glad your doing well and enjoyed your sunny break
girlie hope your bearing up okay it's agony not knowing but I've heard lots of positive stories similar to yours so try and keep your chin up.

I started testing this morning bfn I know its early days but it's sooo disappointing. can't remember when you ladies got your bfp's?
best of luck March and philppa for your testing this week x

Thanks for all the reassurance with flying. I think it's CIS I lost the last one whilst we were away. It will all be fine this time, I'm sure.

Claire, I got my BFP 10 days after ovulation OV 15th, BFP 25th! I thought that was pretty early anyway, but I think some of the others may have been earlier.

Girlie, glad you are a feeling a little more focused. Sometimes it does help to have some plans in mind, it kinda gives you focus either way. I'm up their tues for a quick appt, I'm guessing your in after me this time. Fingers crossed for parking. It is shit, I've even parked over the General and walked across. All though you can't have a free ticket for over their.

Everyone else, keeping things crossed for BFPs.

Ive got a list as long as my arms of jobs to do today, boooring!

Claire how exciting you could be finding out some fab news this week!!
I was 5/6dpo (I've always been early), but wasn't confirmed for trial until 6 days later (I didn't get a positive on site after my initial tests, I didn't know I had to and had just had a wee just before! And it was late afternoon!!)
Yes finding out the sex :). Were going to go for a scan today to find out as you can from 16 weeks, but so many people online have been told wrong so early so we decided to wait til 20. We'll be having a 4d scan about 24/26 weeks so will take ds along and have them properly confirm it!

Size so glad you're enjoying your hol and hope you're feeling relaxed. I don't think the day counting ever goes away!!

Good luck everyone waiting to test so exciting!!!!

Had a great night last night, bed at 2.30am absolutely shattered!!! However still bloody woke up at 8 (dog started barking) dh got up but I was awake then!! Going to be a long day!

Hopefully of things work out and I catch this cycle i won't be flying until 13 ish weeks. When we go to Barcelona I'll only just have caught / be catching if I do so hopefully no impact.

I've already got flight socks. Absolute beauties they are! We honeymooned in Thailand so bought them for that but also used them for New York which we booked to cheer ourselves up after mc number 2. They're actually quire comfy and stop me getting cold feet on the plane!!!

Sorry about the bfn claire, i know it's disappointing but you are super early still. I've never had a positive before 11dpo, and that only with a frer, which are much more sensitive than the trial ones. Don't give up yet! Do you have any symptoms? I have nothing symptoms wise and my positivity is fading! really think it's going to be a bfn this month as last time I did have symptoms and knew before i tested. Although actually i can't remember how soon I had them. maybe it's just too early. Anyway, I start testing tomorrow, but don't expect any result before Friday, probably Saturday more realistically. Good luck for the testing to both you and philippa when you start in a few days x

March I have no symptoms whatsoever but can't recall having any with any pregnancy especially this early. I've never tested before my period before.
I have a strong feeling this isn't my month, not know why just don't think ive caught.
I think my af might be due around next Sun/Mon but I usually spot for 3 days before that (highly annoying)
fingers crossed for you and philippa let us know how you get on.
which tests you got?x

Claire I got my bfp after 13 days so quite a while wait for me.
I always get really weird dreams the week I get my bfp so I had an idea I might. X

Feeling really fed up tonight! Normally I'm a very positive person but today I just feel like I want to crawl under a duvet and not come out. It was my mates little girls first birthday party today and couldn't bring myself to go. It's pretty much 12months since I went round to meet her and told my friends I was pregnant the first time and I think today it's just hit me that 12 months on we're even less close to bringing our own little person home!

I know some of our mutual friends will be being funny that I didn't go but they just don't get it!

Sorry to sound miserable! But I'm hoping some of you can give me some pick me up advice that's worked for you!

Kazz do your other friends know? Tbh if they don't, I'd say something, if they do, I would explain about how you feel.
Totally understand le you didn't go x

Ah Claire I completely get why you didn't go, don't beat yourself up, if your friends know they should be understanding of how hard it is. But I'm guessing non have been in the same situation.
My friends always go on about who's next and they all know so ive stopped going to things if certain ones go as they always make comments !
I feel the same today I just want to stay in bed and cry and just not get up ;(
Xxx

Yeah they do know. I'm quite open about it all but they just don't get it. Theyre always like 'you can't let it dominate your life' but it's near on impossible for it not to!

:( people just don't understand. I read an article the other day I'll try and find it but it helped me ...
Sorry my other message I put Claire instead of Kazz :( sorry
Xx

gardnerquadsquad.com/two-years-ago-yesterday-my-story-with-infertility/
The ladies got endometriosis or something but some of what she writes is spot on. I hope it helps a little it did for me. Xx

I've just read it. Properly choked up. Is the person at the bottom who is now pregnant with quads the same person? That's amazing if so. I know deep down we are very early into our journey. We've not been married 18 months yet. That article does sum things up quite well and made me feel quite lucky to have fallen pregnant three times in such a short time (all within 9 months). Thank you so much for sharing it. It's definitely helped!

I've just got into bed with our wedding album to flick through. Happy thoughts before I go to sleep. And when I do I'll be sending loads of good luck thoughts to you, girlie and the quads lady for the next few weeks.x

Sorry you felt a bit crap yesterday kazz, hoping today brings you more positivity for the cycle ahead. I've also cut off quite a few of my friends who have new babies or are heavily pregnant. I feel terrible about it, but it's self preservation. I've emailed them to tell them why I can't see them at the moment but still feel very shitty for doing it. I know eventually I'll be able to again, but i think it's ok at the moment. If they are good friends they'll understand.

Did my first test this morning. Bfn. Totally as expected, so I'm ok with it. Looked at the tests i have and they are one step midstream (same make as the little ic ones, but you just pee on them rather than having to collect a sample and dip). It doesn't say the sensitivity but if they are the same as the ones that look identical on a Google search then they are 20mlu/ml. Still not as sensitive as frer (10mlu/ml) but more sensitive than lots of high street ones which are 25. Any joy this morning claire?

hi ladies.
hope your feeling a little brighter today kazz? its such a difficult time and I have times where I feel really down about it all. it's so hard to understand if you haven't been here. at least you know we all understand and were hear anytime. I'm feeling pretty rubbish about it all at minute, my twin is due in 2 weeks. the build up and excitement and constant talk of it that's hard then I feel awful for feeling so jealous it's a vicious circle. I'm thrilled for her but can't help but feel so jealous. we are very close but this experience as definitely & unfortunately changed things. in a way once baby arrives it might be easier - God I dont know......gosh I'm rambling now sorry!

bfn here as well March. I expected it too. I'm not sure whether choccy or size once mentioned they are 25?? maybe they can confirm it ladies?x

here anytime not hear!!

Sorry to hear ladies that you've had bfn today, but plenty of days to go.

Unfortunately I've had some bleeding today and together with the scan last week I'm not hopeful. Rung the EPu and they won't bring my appointment forward, so will have to wait until wed to get an answer either way, unless nature takes its own course.

girlie I'm sorry this is happening and that you can't be seen earlier, I hate the whole waiting thing with scans etc I found it so hard. thinking of you x

Kazz yes she is now having quadruplets

March and Claire it's still early I got my positive 2 days before period was due as the tests are poop !
Girlie I'm so sorry hopefully it's nothing, that's not fair they won't change your appt if your bleeding ! Do they not have drop in times you can just turn up ?
I think I am out too I have really sharp pains like I had before my miscarriages and lost all symptoms I keep pushing my boobs and nothing lol. Xx

how any wks are you now Louise?x

6 weeks 3-4 days Claire x

is your scan thurs Louise? I hope all is okay, the loss of symptoms doesn't necessarily mean the worst but I totally get why you would feel like that x