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Conception

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Two out of three cycles of clomid resulted in chemical pregnancies, is there a problem?

16 replies

FingersCrossedLegsNot · 21/03/2013 09:45

So we have been ttc for two years. I have tried three cycles of clomid, I have pcos. The first month and this month (the third) have resulted in chemical pregnancies. I'm starting to worry that there is something more than pcos wrong with me. My gp just put it down to one of those things and as he put it "natural wastage". Is it just one of those things, what experiences have you had with chemical pregnancies, did you go on to have a successful pregnancy. I have a 7 yr old ds so that shows I can get pregnant at least.

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QuietNinjaTardis · 21/03/2013 11:01

Ok I'm no expert at all bhut from reading these boards I think there's another drug they can put you on to help with implantation when you're on clomid. Apologies if I have this wrong and I'm sure someone more knowledgable will be along soon but I think I'm right. Like I say someone who can be more specific will be along soon.

QuietNinjaTardis · 21/03/2013 11:01

Ps love your name!

FingersCrossedLegsNot · 21/03/2013 12:29

Thanks QuietNinja, I have an appointment next month with the fertility doctor so maybe they can shed some light them. My gp is just so flippant!

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QuietNinjaTardis · 21/03/2013 12:36

Fertility doc will know more than gp and hopefully won't be so flippant with you. Goodr luck x

AttilaTheMeerkat · 21/03/2013 13:49

Some GPs know next to nothing about PCOS; its a problem well outside their remit in any case.

I would forget the GP altogether and concentrate instead on your next fertility appt and what you want from it in terms of information. Write down anything you want to ask well ahead of time and remember too that no question is daft. You do not want to be leaving there thinking "Oh I should have asked about xyz".

If at all possible, do not go to this next appt on your own. Your man needs to attend this with you.

Metformin given in conjunction with clomid can be an effective combination.

Clomid is often the first line of treatment given to those with PCOS but it is not suitable for all to take. Clomid resistance can occur, its main job is to make the ovaries work harder. It can also increase LH levels markedly so monitoring is vitally important. No monitoring therefore is unacceptable.

I was not offered clomid at all (I have PCOS) because it would not have helped me (the consultants words). I was told by my cons at the time that my own personal risk of miscarrying was actually far higher.

I would certainly ask them about other treatment options going forward like injectible drugs and ovarian diathermy surgery.

QuietNinjaTardis · 21/03/2013 14:03

I knew someone more knowledgeable would be along soon Grin

AttilaTheMeerkat · 21/03/2013 14:10

Oh you are too kind honestly Blush

OwnedByACockerSpaniel · 21/03/2013 14:19

I had 3 chemicals off clomid, also have PCOS but no insulin resitance so was not prescribed Metamorfin. I'm known as a thin pcoser.

Anyhoo, for me now 11 miscarriages later it transpired after MC number 5 or 6 I cant remeber Blush that I have a genetic abnormality. A balcance chromosonal translocation. I am fine because it is balanced however it means 50% of my eggs are useless they contain too little or too much genetic information to create a viable offspring. Now out of the 50% I have left half will result in a baby with a balnced translocation like me, meaning she/he will face fertility issues and the other half will result in a "normal" genetic make up and a "healthy" offspring.

How old are you can I ask?

I am in my 20's and so a karyotyping was done to look at my genes, as a woman of my age should not have so many losses.

There are other scenarios for early loss, such as a problem with the immune sensitive, it can sometimes be a little sensitive and attack the embryo killing it, medication can be given to stoip this. Also sometimes clomid can cause a poor quality lining of the womb meaning implantation can not occur, if this is the case perhaps asking to try femera as it has the same effect on the ovaries as clomid but does not have an effect on the womb lining.

Write every question you can think of on a piece of paper, and work through them with your consultant. Good luck Grin

FingersCrossedLegsNot · 21/03/2013 14:34

Thanks for the responses, they were very informative. I am 28, I'm taking 100 clomid for the last three months without being monitered. I am also taking metformin. The clomid seems to be working as I am finally ovulating. My day 21 results were, first month 28, second month 44 and this month 108 that is up from 5 without clomid. I just feel like giving up now, they are not even that great in the hospital as I'm not going private. I think I may have to change to private. As it seems no one listens to me going public, I'm just a number.

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OwnedByACockerSpaniel · 21/03/2013 14:48

3 cycles back to back Shock my dr never lets me do this its always been a medicated cycle, then a break then another medicated cycle! I would put my money on clomid ruining your womb lining. Give it a break for a bit, take baby asprin daily then when your next cycle comes clomid it along with the baby asprin..

Don't give up sweetie! I've been playing the TTC game for 5 years now, you will get there.

Sit down with your consultant and tell them how you feel about it all, they sometimes forget to take people as individuals as they see hundreds of people.

You will get there! After 4 cycles of failed clomid you should also be able to progress to IUI they may be doing this, just getting past the clomid stage.

Massive hugs hun, you will get your baby xxxxxxxx

FingersCrossedLegsNot · 21/03/2013 14:58

OwnedByACockerSpaniel you know I was actually just sitting here wondering if I should take a break from clomid as it could be having an effect on my lining. AF has been very very light recently. I will also defo take the baby aspirin. They actually have told me I am to take 6 cycles of clomid one after the other!

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FingersCrossedLegsNot · 21/03/2013 15:00

It's a horrible thing this ttc especially for a long time it consumes all my head space....but I'm too obsessive to stop! Blush Best of luck to you also....have a any dc or is this your first your ttc? X

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OwnedByACockerSpaniel · 21/03/2013 15:04

Shock NOOOOOO!

light AF is normally a sign of a poor/thin lining. 6 back to back is absurd, you might build up resitance to it like that also.

Right I never told you this Wink

Take the clomid off them as they prescribe, dont use it for a cycle. Phone them say CD6 and say "oh I have completely frgotten to take it" They will abondon the cycle. Take the baby asprin give everythign a rest. When AF comes, if it normal not light, take your clomid next cycle. If it's still light have another months break but this time you will have to be more inventive about the reason for not taking it, say you went on holiday and forgot the pills OOOOOPS. Then again asses AF.

I have never done this Wink

OwnedByACockerSpaniel · 21/03/2013 15:05

No DC Sad but I will get one and me and DH have decided we will have one biological child but the rest of the siblings can be adopted childre. We just want to experience pregnancy and so forth. It's not about loving a biological child more or anything, just wanting that major life experience.

FingersCrossedLegsNot · 21/03/2013 15:33

Good plan.... I won't tell a soul Wink We were also considering adoption, like you it's just about wanting a child it doesn't have to be biological. But I will let this ttc run its course first.

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AttilaTheMeerkat · 21/03/2013 15:40

Thin womb lining (have had this) is also linked to PCOS: think I had this due to not enough progesterone being produced.

Its appalling that you have not been at all monitored; infact they have failed here by not doing that.

You will need to be persistant in order to get answers; I'd give this current unit you are being treated at a wide berth. It is fair to say that in the NHS some fertility units are far better than others.

If you did go private I would urge you to do your researches thoroughly beforehand and not get taken in by the better surroundings. Some private treatment can be poor as well as expensive; be careful.

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