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Conception

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IUI tomorrow - do you know anything about follicle size and lining?

5 replies

lucylookout · 13/05/2011 19:30

Hi, I'm 39 with low ovarian reserve, DH has high count (98 mil) but 2% morphology. We have IUI planned for 10am tomorrow morning but my head is buzzing with so many unanswered questions and was wondering whether some of you might be able to help.
I took letrozole from days 2 - 6, then went in for my first scan on day 7. Dr told me that there was only one follicle (instead of the 2 or 3 we'd been aiming for), that it was too big and the lining was too thin (5 mm). All in all not a good appt. He sent me away, telling me to take 3 Gonal F shots (Tuesday eve, Wed morning and Thurs morning). I went back yesterday evening, day 9, and the lining had thickened to 10mm and the follicle was a whopping 25mm. I took stim shot last night at 11pm and IUI is tomorrow, day 11. So, I came away thinking, ok, only one follicle but at least it's big, all the easier for DH's swimmers to find, surely, Wink but then having consulted google (I know, I know, I should have stayed away), it looks like a follicle this size is borderline too mature and is unlikely to be able to be fertilized. Is this true?
Also, do you think, is it the drugs that made this follicle grow so big so early? So, even though I only produced one, the drugs made it bigger, faster than usual.
Has anyone had similar results to this and (amazingly?) got pregnant? Or has anyone had similar results to this, had their drugs changed and gone on to have IUI success? (or indeed anyone with low ovarian reserve who has had success with IVF instead).
Obviously a lot of it will come down to what DH's sperm is like once washed, but I'm wondering whether Dr should have triggered me earlier, or indeed even called this cycle off.
Also, he didn't do a baseline scan at the beginning of the cycle, and at the end of the appt yesterday muttered something about maybe he should do one at the beginning of the next cycle to make sure there's nothing there. Does he mean he thinks my whopping follicle could be a cyst?
Sorry for such a long post, full of lots of questions, but I'd really appreciate any advice/experience/reassurance anyone has Smile

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lucylookout · 13/05/2011 19:34

oh, and also, no EWCM this month. Is that the drugs? I know clomid can dry you up but I didn't think letrozole had any effect. I drink loads of grapefruit juice and take EPO so normally have a fair bit Confused

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gardenpixie · 13/05/2011 19:43

Lucy, I'm afraid I don't have any actual advice but wanted to say a gynae consultant I was seeing for clomid said a follicle up to 27mm on a medicated cycle is viable ... Some non medicated follies get even bigger.

So you have a lovely big egg waiting to meet your the washed swimmers and 10mm sounds like excellent lining depth ... A nice soft bed for your embryo to nestle into for the next nine months.

Very very best of luck tomorrow Smile

lucylookout · 13/05/2011 20:25

Thanks gardenpixie, that's reassuring. I've been lurking in your thread a bit too, best of luck with the IVF Smile

Does anyone else know anything about this?

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imabiggirlnow · 13/05/2011 20:42

Hi Lucy, I had a very similar cycle to you also on the letrozole although took much longer for the follicles to develop (unbelieveably about 3 weeks!) I was booked in for IVF but only 1 follicle developed so they decided to do IUI instead. I was so disappointed to only have one and I thought they had left it to late as previously there had been more. From memory it was about 22mm - I had had a previous cyst and was worried it was another one but I guess they can tell? Anyway to cut my wittering short I had the IUI and now have a beautiful boy who is nearly 3! After the IUI I carried on life as normal but did drink loads of full cream milk, think ate brazil nuts for some reason and had acupuncture on the day of implantation (really think this works as had another baby last year after doing the same thing). Really hope it works for you too, afterwards I really did feel they knew what they were doing and I should have trusted them more!

lucylookout · 13/05/2011 22:32

Hhhmm, that's encouraging biggirl, thanks. When did you have acupuncture? 6 days later? I have a session booked in for Monday, so hopefully that will help a bit.

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