It's hard to cull the list...mine is just over 50 and I have tried over the years.
I have a list. I start around now looking through what I have in my "gift box" of things to regift (to other side of the family or not family - and that recipient would enjoy), and start ticking off people that way.
I try and buy 1 a week from now (I do a Holiday Grand Plan from end August to clean house top to toe, decorate, and otherwise prepare for the entire Christmas season). I have a few overseas ones that I have started trying to find local stores to them that wrap and deliver.
For the "bottle of champers" people, I try and go to a good wine merchant in the autumn for both nice bottles to gift and nice wine for Christmas for our house (I get 2 really nice bottles for Dh and I for Christmas Day - we might open the 2nd if we are enjoying it so much, but often it's left for another time, but I don't mind spending more than usual for something we would enjoy).
Also, I will be ordering good hot chocolate mix from an artisan supplier we've used for years for here, and add posh hot choc (lump of chocolate on a wooden spoon) stirrers for various DCs to make "just" a book or small toy more special.
I love a good browse in a good bookshop for books for DCs especially, and often find good ones for adults too. So set aside a couple of lunch breaks to visit a good one near work in Oct/Nov usually. And come back laden down.
There are a few craft fairs locally in early December that can be useful - sometimes I see things for someone I've already bought for, but might buy anyway and add 1 of the options to the gift box in storage for the next time instead.
Family hampers (movie night incl dvd, popcorn and snacks; games night board game, deck cards, extra dice, snacks; saw an Ice cream sundae bar idea recently of all the toppings to add and nice bowls) can be nice sometimes. I tend to give them 1 year and individual presents again the next, not every year unless they really react positively to it.
And sometimes individual hampers focused on their interests are good - small but n ice versions of useful items, and things related to that interest that get used up etc. So someone who sees might be a small scissors, magnetic pin holder abs extra pins, set of fat quarters and a matching thread/2, handful of nice trimmings etc. Or a baker maybe some precut liners for tins, a few nice cutters in different shapes, interesting essences or colours for icings etc. Similar for a gent - could do golf with disposable hand warmers, tees, golf balls and a small club towel or covers for the woods; a set of different whiskey miniatures with some funky shaped ice cube makers and some bar snacks or a really nice glass; etc. Eco themed for teens or young adults could be good.
And setting aside a couple of evenings in early December to do the wrapping, have plenty of supplies of paper/tape/tags, ribbons or decorations, etc - and also bags. Gift bags might be useful to wrap. But also have a bag (paper shopping bag is fine) to put together all presents for a family or group as you do them. Makes it easy when it comes to packing for post, dropping off to houses, bringing to gatherings or grabbing as you dash to school on last day...etc.
Just because you find a cool thing on 1 website, doesn't mean you can't buy a few and use it for different people in different parts of the list - so a particular lovely scarf could do a lady in your family, another in DHs family, and a great friend - in colours to suit each recipient - but all the same and just 1 order. Especially if there's an offer on buying more than 1. Even if you don't like repeats generally, doing it for different groups on the list mean others won't see the repeats.
Apologies for any typos as doing this on my phone.