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Pre-school booster jabs side effects?

3 replies

Thisisfinethisisallfine · 20/01/2026 04:34

My 3 year old had the 4in1 and mmrv yesterday morning (9am) and was completely normal all day - eating, running around etc. But then woke at 3am with tummy pain and has been sick a couple of times, is this a normal reaction? Or have we been unlucky and picked up a bug?

Are your children’s vaccines up to date?
ChipDaleRescueRangers · 21/01/2026 06:57

It could be either to be honest.

NHSVaccineNurses · 19/03/2026 10:28

In partnership with NHS

Most side effects are mild and short-lived. Giving your child plenty of fluids, a comfortable environment, and over-the-counter medicine like Calpol can help.

Most children handle these vaccines very well, and serious problems are extremely rare. Some mild reactions are normal and a sign that the immune system is responding:

Measles, mumps, rubella and varicella (MMRV) vaccine:

  • Mild fever (usually 1-2 days after the jab)
  • Sore arm or leg at the injection site
  • Mild rash (usually a few spots, appearing 5-12 days later)
  • Temporary irritability or tiredness

4-in-1 booster (diphtheria, tetanus, pertussis/whooping cough, polio):

  • Sore arm or leg at the injection site
  • Mild fever
  • Fussiness, tiredness, or decreased appetite

When to seek medical help:
Contact your GP, NHS 111, or seek urgent care if your child develops:

  • High fever (over 39°C / 102°F) that doesn’t settle with usual measures
  • Persistent crying or unusual drowsiness
  • Severe swelling, redness, or hard lump at the injection site that worsens
  • Any signs of an allergic reaction: swelling of face/lips, difficulty breathing, widespread rash

Most children bounce back quickly and feel fine within a day or two. Mild reactions like a low fever or tiredness are normal and temporary. Vaccines are thoroughly tested for safety and protect your child from serious illnesses. Remember, these brief side effects are far outweighed by the long-term protection your child gets and seeing them back to their usual cheerful self within a couple of days is very common.

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