Omeprazole/Losec Mups?

[ihearttc]

Just after some advise if possible? DS2 who has just turned 3 has been prescribed Losec Mups by the hospital.

Its proving a huge faff to get them into him. Dr suggested mixing with juice but he won't drink juice just water so have been letting them dissolve in a syringe with some water and getting them into him that way. The problem is that he has to have 10mg a day but spread over 2 doses (the reason he has been prescribed them is specifically to keep the acid away from his throat/larynx) so it needs to be covered for the whole 24 hours so I have to give it morning and night. He still has milk in the morning and before he goes to bed and as I understand it they can't be mixed with milk but does that mean you can't drink milk within a certain time of taking them?

On top of this Ive got to give him Gaviscon Advance 3 times a day after every meal (which at the moment he is completely refusing and I don't blame him as its revolting!) so it seems like all Im doing is giving medicines all day long.

Dear ihearttc,
sorry but I don't have much idea about the reason why milk cannot be taken with the meds, but I used to be prescribed Lansoprazole & Omep. until recently. also took Gaviscon thrice daily...
What I'm trying to say is I wish I could help, but I am here to hold your 'virtual' hand. If you are facing difficulties or have unanswered questions, why not ring 111 if you're in the UK? It's a brilliant service if it's no yet available in your area, try the out-of-hours doctors' Clinic All the best. X

I would go back and ask for lansoprazole solutabs. They aee strawberry flavour and dissolve in the mouth. A bit gritty but taste-wise fine.

Did your doc mention that they need to be taken 30 mins at least before food?

Nooooo he didn't-bit of a long story but we haven't even seen our GP about them. The consultant at the hospital gave them to us...bit of a last ditch attempt to try and avoid complicated surgery. So I had to take the letter with the request for medication into the doctors and they just gave us a prescription. Pharmacist didn't say that either just said to avoid mixing with milk. So Ive been giving them in the morning about an hour after breakfast and then at night about an hour before bed. Will they not work then if its not taken 30 mins before food?

To explain why he needs them might help I guess! He has got an ARSA (Aberrent Right Subclavian Artery) which basically means one of the arteries from his heart has come off the Aortic Arch in the wrong place and its pressing on his Osophagus and Trachea. They think where the artery is pressing its causing Laryngopharngeal Reflux and the acid is irritating his larynx causing a stridor like noise and constant cough. Only other option is major heart surgery to completely reposition the artery.

He is taking it ok with how we are doing it...he is really good with medicines and doctors etc but its a huge faff so those other tablets sound much better. Will see if I can attempt to get an appointment before christmas. Thank you so much for your help.

Hi . Dd is 10 and we went through a difficult time a couple of years ago and although she took tablets fine before this after different interventions she refused to take tablets. We use fastab which are strawberry tasting and melt on the tongue. Other brands which melt arent as easy to tolerate according to dd so we always get fastab. Agree about you need to take them half an hour before eating and on empty stomach.

Seems strange, OP. My DS has been on them for six years, at one time on 30 mg a day. My understanding is they have a very long activity time (wrong definition!) so, for example, when DS had to have a pH probe test, he had to be off the Losec for a week so that its effects wouldn't be felt.

(I noticed on the sheet that things like Zantac were much shorter).

Having said that, when he was on 20 or 30 mg a day, we did split it into two doses, but that was more that his tummy seemed to be affected by having too much at once, rather than the reflux.

(My DS has it for classic reflux associated with his wider condition, so obv very different to your DS.)

Also we have always given it at the same time as his milk feeds (he was wholly tube-fed until he was four, still partially tube-fed). His gastro has never said about timing it 30 mins before feeds, although when DS was on domperidone, he was emphatic about it with this.

It sounds like it might be worth phoning the consultant's office and seeing if you can talk to them for clarification. I hope it gets sorted.

(Blimey, am a bit worried now we've been doing it wrong for 6 years! But it has worked - without question.)

Yes, I would definitely say ask them what they want you to do WRT taking it before or with food. With DS they always said to do it before food, as food interferes with its absorption. Maybe the advice has changed though. The GP would know (or so you would hope). Also, it might be different for different formulations.

It can be normal to give split doses of PPIs (like omeprazole) for GERD - this is popular in some US clinics IIRC. But seriously, the lansoprazole is easier to take. I used to literally rub it inside DS's cheek and then get him to wash it down with some water.