This is a very interesting article regarding fever reduction in children. NICE (National Institute for Clinical Excellence) is still recommending using only one anti fever med. This article from the BMJ (British Medical Journal) news.bbc.co.uk/1/hi/health/7592585.stm
is now saying this advice is not as effective and children are kept fever free for an extra 4 hours with alternating calpol and ibuprofen.
NICE's main objection seems to be the risk of overdose, but most sensible parents would keep a record of whats given and when, expecially if they had a houseful of sick kids!