Frakkit said it well - it is a very different dynamic.
I sort of have that situation, I work part time at home and have a nanny present.
At the moment I have a fairly flexible handover, in that for the first half hour I gradually hand over the children to the nanny by finishing whatever it is I'm doing with them. Over a period of time this has worked out quite well, the duty handover is almost automatic - in my particular case I finish the breakfast off with them while the nanny begins tidying up some of the breakfast dishes (or joins in for a cuppa) then when breakfast is finished I take off to get ready for my day, after listing anything specific that needs to happen that day.
You also need to plan activities ahead - I have chosen most of the regular activities/classes the children do (a music class and a swimming class each), and generally take one of them while the other is left with the nanny, but this is clearly scheduled ahead - 1 one 1 time with the children is part of the reason why I chose to have a nanny.
If there is anything else I specifically want the children for then I set that out and let the nanny know as well -large outings are so much easier with 2 DC when both nanny and I are present. I also let the nanny know whether I will be in or out of the house, or generally what I will be doing/want to accomplish. If I am pottering around in the garden one afternoon my DS1 will almost invariably want to be outside with me, so easier to not fight it and let him 'help' while nanny looks after DS2.
If there is a particular activity that the nanny wants to take the children to she will check in advance what day will be better for me/them and we list that down in the diary.
Nursery duties are scheduled for the mornings when DS1 is at his nursery (for his free sessions) and when DS2 is napping.
It is VERY difficult to not become 'friends' with your nanny, and the repurcussions that come from that. There will always be times when you need to be the 'employer', especially if you're not happy with the way something is happening - which given that you are occupying the same space will always happen. After several false attempts at dealing with a particular problem, I eventually presented the problem to the nanny (for the umpteenth time!!!), told her that clearly my suggestions weren't working but the problem absolutely needed solving, and that she needed to go away, think about it, and come back on X day with a solution as to how SHE wanted to fix the problem. So far this has worked.