I agree with calmlychaotic up to a point! I would say it is vital not to be panicked into taking on any work no matter how unsuitable, but on the other hand if it is proving hard to break in to minding in your area, there is nothing wrong in my view in being a bit more flexible than the majority, if you are able to do that with your family commitments, but viewing it as a strategy to get a few customers and some good feedback under your belt. I think it is fair to say that many parents will tend to choose minders who already have some experience and one with a child or two already on the books over one with none - and that is understandable as a lot of newly-registered minders pack it in quite quickly when they hit problems or can't make the finances work.
If you get yourself known to your local authority children's services, they may contact you when parents come to them looking for childcare advice or having trouble finding childcare. For example, you may be ideally placed to take on siblings, as larger families often find it difficult to find someone who can offer places to two or more children at once. I took on a couple of "difficult to place" children when I first started and it was actually very rewarding, in terms of experience if not financially. I am still friendly with one of the mums three more children down the line, and I know she has given me glowing reports to friends and relatives. I have also since had a number of council staff come to me for care of their own children, including the manager of the children's centre. I still do emergency care, both privately and for the council. If I am quiet, I happily take children for the odd day or two or just a few hours, and this has resulted a couple of times in families coming back to me later when they have more regular childcare requirements.
So, to sum up, I'd say do what works for you, but do it with your eyes open! Good luck.