Mifepristone Induction trial - would you do it?

[Pregandcounting]

I have been offered to take part in the MOLI trial (Mifepristone Outpatient Labour Induction). I’ve been doing some reading on mifepristone for the use of induction, but am curious what others think or any useful info anyone else has found?

I’ve read about this trial.

I would want to know what monitoring they’re going to provide to ensure safety. It’s not a currently used induction method, so why are they doing it as an outpatient rather than inpatient with extra monitoring

Isn't that one of the meds used for terminations?

I thought that. I’m sure it’s the one that makes your womb contract in order to pass the pregnancy.

Yes it is.

I think the best thing to do is chat to the research midwives at your hospital. Read the patient information sheet (PIS), and make notes. Ask to read the protocol, if you're able to (it will be dense). What are the risks - and are there any benefits to you taking part? The research team's job is to help you make sense of it all. Taking part in research can offer benefits to the patient but a part of participating sometimes just comes down to altruism on the part of the patient. The sponsor will fundamentally have an important question that you would be helping to answer. But never if it compromises your personal sense of safety.

Reading the study info it looks like you'll be receiving the standard NHS maternity care with both the Mifepristone and the placebo, so doesn't seem like there are any benefits in terms of increased monitoring, dedicated team etc?

I've been induced as an inpatient with the other abortion drug misoprostol, and I'm grateful I was in the hospital as I ended up with uterine hyperstimulation and (thankfully) an epidural. So after that experience I would be wanting to find out if there were any increased risks of hyperstimulation, though it maybe looks like the risks are lower for oral delivery?