eStar
"FWIW, she is my fifth child and all the others managed to survive such neglectful milk-mixing too...."
God I hate that argument - it is worth nothing! This is mainly a low incidence but high risk problem - i.e. it doesn't happen often but when it does it is catastrophic.
The increased risks of D&V generally amongst FF children are caused by the "less harmful" bacteria and unsafe feeding practices.
"Powdered infant formula (PIF) contaminated with harmful bacteria has been implicated as a source of illness in infants. In recent years, the emergence of disease associated with a bacterium, Enterobacter sakazakii, in PIF has necessitated a new risk assessment.
The Food and Agricultural Organization of the United Nations (FAO) and the World Health Organization (WHO) have hosted two joint risk assessments on the subject (FAO/WHO, 2004 and 2006). One outcome of
these risk assessments has been a risk assessment model that has allowed for the examination of the relative risk to infants of different practices regarding the reconstitution of powdered infant formula and ensuing infant feeding practices. As a result of this work, the WHO has issued new
guidance on infant feeding (WHO, 2007)."
"Invasive E. sakazakii disease is not a common occurrence in infants.There have been approximately 60 reported cases of E. sakazakii infection worldwide since 1958 (Mullane et al, 2006). However, there is concern that it has been under reported. In 2003, a United States FoodNet survey
estimated the annual rate of invasive E. sakazakii infection to be one per 100,000 infants (children less than 12 months of age) (U.S. Centres for Disease Control and Prevention (CDC) unpublished data).
In infants of very low birth weight (less than 1,500g) the incidence was estimated to be 9.4 per 100,000 in a study of 19 neonatal intensive care units (Stoll et al, 2004). Children greater than 12 months of age and adults are thought to be a much lower risk group than infants. E. sakazakii has been associated with neonatal meningitis, necrotising enterocolitis (NEC), bacteraemia and necrotising meningoencephalitis (Muytjens et al, 1983; Iversen and Forsythe, 2003). Reported mortality rates are high; NEC 10-55% and meningitis 40-80% (Iversen and Forsythe, 2003).
A U.S. Centres for Disease Control and Prevention (CDC) report investigated the risk factors relating to ingestion of E. sakazakii in infants (Bowen and Braden, 2006). Forty-six cases were analysed (12 with bacteraemia, 33 with meningitis and one with a urinary infection). The infants
with meningitis tended to be near-term infants (median 37 weeks) of normal birth weight (median 2,454g) where infection tended to occur soon after birth (median six days after birth).
The infants with bacteraemia tended to have very low birth weight (median 850g), were pre-term (median 27.8 weeks) and developed infection after the first few weeks of life (median 35 days). Bowen and Braden concluded that their findings suggested that all neonates (infants ² 28 days) as well as premature infants should be included in the ?high-risk? infant category. FAO/WHO concluded that the high-risk group are all infants in the first two months of life (FAO/WHO, 2006) based on the knowledge that infants up to about two months are known to be at elevated risk for meningitis (Dr. A. Bowen CDC, pers. comm.)."
All taken from the Irish link I posted above.