I had a nuchal scan with all the blood biochemistry stuff done at the fetal medicine centre just over ten days ago. The NT was 1.4mm, a nasal bone was present and there was no leaking of the tricuspid valve in the heart..... so far excellent. In spite of my advanced years (43) it gave a very favourable result, something like 1 in 360 (can't remember exactly). However,they then factored in my blood results and due to higg HCG and extremely low PAPP-A (mostly the low PAPP-A I think) I ended up with a result of 1 in 7. After very careful consideration we decided to return to the Fetal Med centre (2 days later) and have a CVS. Professor Nicolaides did the CVS and he was excellent. We got the result back two days later by phone and everything is absolutely fine. Just something odd about my blood I think! If anyone is going through the same thing, I thought that this might help. The CVS was very temporarily uncomfortable but not painful. I had minor cramping afterwards and no bleeding. I think it makes a huge difference having someone experienced doing any invasive testing. There was minimal fuss and I had total confidence in him and his staff. We did find out that the baby is a carrier for Cystic Fibrosis which means that either I am a carrier or my DP is a carrier. Does anyone have any experience of CF carrier mutations?