Hi there, August sisters. This isn't "my" thread, I belong on the June thread, but I just want to share a little nugget of information with you in the hope that it might save someone some worry along the way. If it has already been covered here, I apologise for doubling up, I just couldn't read all 11 pages 
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I know not everyone will choose to (or have chosen to) take up the offer of prenatal screening (the NHS combined test in particular), so this only applies if you are looking in the direction of such screening.
I received what I considered to be a high risk for trisomy 21 when my results for the combined test came back before Christmas. Knowing that invasive diagnostic testing (such as a cvs or an amnio) carries with it an inherent risk of miscarriage, however small, I spent a sad and frightened day wrestling with how to proceed, very much feeling like I wanted to know if my baby was OK, without risk to the much-anticipated pregnancy. Late that night, after lots of phonecalls and googling and with a heavy heart, I chanced upon a thread on here (good old MN) about the Harmony Test (it's running in the ante-natal tests and choices forum). Now, in mid December, this was only just being introduced in the UK and certainly wasn't very well known. Perhaps things have snowballed and it is now a better known procedure, but just in case someone doesn't know, I'd love to share the possibility of non-invasive screening with a high accuracy rate.
The Harmony test analyses "cell free DNA" which is basically fetal DNA present in the maternal blood stream, and is able to to pick up, with a remarkably high accuracy rate (99.6 %) evidence of trisomy 21 (DS), 18 and 13. The procedure which, I believe, can be done from 10 weeks and onwards (I was 15+4), involves a simple bloodtest (from your arm) and an ultrasound scan. The bloods are sent to the US for analysis, as there is as yet no laboratory in the UK with the necessary facilities. Results take a fortnight. The downside is that it is so far only available privately, as far as I know in London (The Harley Street Centre for Women, The Fetal Medicine Centre, The Birth Company and possibly others) and in Cardiff (Spire), and comes with a matching price-tag 
(prices vary, but appears to be roughly the same; £400 for the blood test and £170-£210 for the scan, depending on how far along your pregnancy has progressed). None of these clinics actually advertise the test on their websites yet, so it is best to ring them directly.
I had mine done at The Harley Street Centre for Women, with the thorough and knowledgable Dr Pandya. I cannot praise them enough; very professional and efficient, yet very warm and accommodating; the admin team doted on my travel-weary 2 yo DD (we'd been on the road all day) and plied her with chocolates, the nurse let her "help" take my bloods, Dr Pandya was well versed in all things Peppa, and expertly multi-tasked; taking his time to answer all my questions with patience and kindness and performing a reassuringly detailed scan while keeping up a polite chat with DD. I really felt I could not have been in better hands (but then I had done extensive research into his credentials before booking).
I had my results today, I feel confident that they are reliable and I would whole-heartedly recommend this procedure to anyone who is worried about the results of their combined test but who doesn't want to risk invasive diagnostic testing. I am aware that the price is a considerable obstacle; for me, the possibility of peace of mind won out, we've made some sacrifices in other areas.
Whereas I kind of hope I have posted this in vain, and that nobody will receive anything other than the screening results they were hoping for, I also hope that it may be of interest, should anyone find themselves in unforeseen circumstances.
Best of luck to all!