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Autoimmune disease

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C-reactive protein (CRP) low so Doctor said it's not autoimmune?

9 replies

MovingAgainOhWhy · 03/04/2018 17:44

I posted before and have been having health problems for a while. But in the last year I have had tingling legs, muscle cramps, joint and muscle pain, eyesight problems, bladder issues, fatigue and developed Asthma. (Doctor thinks Asthma might be unrelated to the rest). I had an MRI of brain and spine and am waiting for the results.

Anyway, I questioned my GP about possible autoimmune conditions as I have Lupus (SLE) and RA in my family.

He said as my CRP test result was very low autoimmune is unlikely. I have had lots of routine tests and my results could not be more perfect tbh. But I haven't had any other blood tests for specific autoimmune conditions.

So my question is, does low CRP mean I definitely don't an autoimmune cause to my symptoms?

I ask as I know how difficult it is to determine autoimmune conditions through blood tests.

I would love to hear other peoples experiences of this

thanks

OP posts:
Ubercornsdiscoball · 03/04/2018 17:45

CRP won’t be a measure of an autoimmune condition unless you are experiencing a ‘flare’

Sunshineworshipper · 04/04/2018 22:45

As above poster said an active flare would usually cause high CRP. However, I have auto immune diseases but never have a high CRP. It depends what type of disease aswell. For example someone with MS may not even have a high CRP, even during their flare.
Have u had your vitamin levels checked vit d or b12? Sometimes when they're low they can cause A LOT of problems.

MovingAgainOhWhy · 05/04/2018 13:38

Thanks that's interesting to know!

I am pretty sure I don't have a B12 deficiency as my GP checked for that specifically, I think the blood test said my B12 was high within the normal range. Same for Vit D.

OP posts:
Backingvocals · 05/04/2018 13:41

I think that's too simplistic. I have an auto immune condition and my CRP is pretty stable. It's always slightly above the reference range but only slightly.

MargoLovebutter · 05/04/2018 13:42

Moving, ask for a copy of the results and check where in the range your results fall. GPs will say results are normal, even when the result is dragging its arse right at the bottom of the huge ranges used. You want to be aiming for optimal levels of all vits & minerals (at least half way in the range). Have they checked ferritin levels too?

MovingAgainOhWhy · 05/04/2018 20:28

Hi Margo I did get a copy of my recent blood tests, vit b was 514 (normal range 187-883 ng/L) which I thought was pretty good? I can't find my other blood test results but Vit D was very good and I think so was ferritin (I was checked for anaemia specifically before). I have a very good diet and take lots of supplements and GP doesn't think my problems are related to vitamin levels, my vit levels are always very stable and not ever on the low side

OP posts:
MovingAgainOhWhy · 05/04/2018 20:51

Just read up on Vit B12, even though I don't think mine is low enough to cause the severity of some of my symptoms I realised my multi-vitamin doesn't have much in so I might switch to a more comprehensive one. Looks like some countries put 500 as their min, so mines close to that and I wouldn't mind an energy boost at least!

OP posts:
MovingAgainOhWhy · 05/04/2018 20:53

Thanks Backing it's interesting to hear your experience. It seems the CRP issue is pretty complex

OP posts:
PeppaPigTastesLikeBacon · 11/04/2018 21:59

CRP is a measure of inflammation.

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